Pal Priyankar, De Hriday, Giri Prabhas Prasun, Ganguly Nupur, Mandal Alolika
Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.
Indian Pediatr. 2019 Jan 15;56(1):73-74.
Idiopathic pulmonary hemosiderosis is conventionally treated with steroids, prolonged usage of which maybe deleterious and disease often recurs on tapering. We initiated hydroxy-chloroquine and azathioprine early in treatment along with steroids in seven children with idiopathic pulmonary hemosiderosis, and observed that early introduction of second line immunosuppressants helped in reducing disease flare and steroid toxicity without serious adverse effects.
特发性肺含铁血黄素沉着症传统上用类固醇治疗，长期使用可能有害，且疾病常在减量时复发。我们对7例特发性肺含铁血黄素沉着症患儿在治疗早期就开始使用羟氯喹和硫唑嘌呤并联合类固醇，观察到早期引入二线免疫抑制剂有助于减少疾病发作和类固醇毒性，且无严重不良反应。
