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血液透析单位中的丙型肝炎:诊断与治疗方法

Hepatitis C in Hemodialysis Units: diagnosis and therapeutic approach.

作者信息

Constancio Natasha Silva, Ferraz Maria Lucia Gomes, Martins Carmen Tzanno Branco, Kraychete Angiolina Campos, Bitencourt Paulo Lisboa, Nascimento Marcelo Mazza do

机构信息

Associação Renal Vida Rio do Sul, Rio do Sul, SC, Brasil.

Sociedade Brasileira de Nefrologia, São Paulo, SP, Brasil.

出版信息

J Bras Nefrol. 2019 Oct-Dec;41(4):539-549. doi: 10.1590/2175-8239-JBN-2018-0177.

Abstract

According to data from the last census of the Brazilian Society of Nephrology (SBN), the prevalence of hepatitis C virus (HCV) in Brazilian hemodialysis units (HU) is 3.3%, about three times higher than what is reported for the Brazilian general population. Often, professionals working in HU are faced with clinical situations that require rapid HCV diagnosis in order to avoid horizontal transmission within the units. On the other hand, thanks to the development of new antiviral drugs, the cure of patients with HCV, both in the general population and in patients with chronic kidney disease and the disease eradication, appear to be very feasible objectives to be achieved in the near future . In this scenario, SBN and the Brazilian Society of Hepatology present in this review article a proposal to approach HCV within HUs.

摘要

根据巴西肾脏病学会(SBN)上次普查的数据,巴西血液透析单位(HU)中丙型肝炎病毒(HCV)的患病率为3.3%,约为巴西普通人群报告患病率的三倍。通常,在血液透析单位工作的专业人员会面临需要快速进行HCV诊断的临床情况,以避免单位内的水平传播。另一方面,由于新型抗病毒药物的研发,无论是普通人群还是慢性肾脏病患者,HCV患者的治愈以及疾病的根除在不久的将来似乎都是非常可行的目标。在这种情况下,SBN和巴西肝病学会在这篇综述文章中提出了在血液透析单位中应对HCV的建议。

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