Ierardo Gaetano, Mazur Marta, Luzzi Valeria, Calcagnile Francesca, Ottolenghi Livia, Polimeni Antonella
Department of Oral and Maxillofacial Sciences, Sapienza University of Rome , Rome, Italy.
Cranio. 2021 Jan;39(1):58-64. doi: 10.1080/08869634.2019.1581470. Epub 2019 Feb 26.
: Treatment of sleep bruxism (SB) in children is not well established. The aim of this study was to develop evidence-based recommendations on SB therapy in children between the ages of 2 and 17. : A systematic review and meta-analysis was conducted. Literature searches were performed using MedLine (PubMed), Web of Science, Scopus, and the Cochrane Library (November 30 2017). : The search strategy identified 268 potential articles; 10 papers were included in the qualitative synthesis and 3 in the meta-analysis, for a total of 94 patients. Hydroxyzine therapy showed the strongest efficacy on SB (OR 10.63; CI 95%, 1.48 to 76.08). Flurazepam and Melissa officinalis therapies presented lower grades of association with decreased SB symptoms. : Data on treatments of SB in children are limited. Future studies with a proper design, conducted on a meaningful number of patients, and based on standardized and developed diagnostic criteria are desperately needed.
儿童睡眠磨牙症（SB）的治疗方法尚未完全确立。本研究的目的是针对2至17岁儿童的SB治疗制定基于证据的建议。：进行了系统评价和荟萃分析。使用MedLine（PubMed）、科学网、Scopus和Cochrane图书馆（2017年11月30日）进行文献检索。：检索策略共识别出268篇潜在文章；10篇论文纳入定性综合分析，3篇纳入荟萃分析，共计94例患者。羟嗪疗法对SB显示出最强疗效（OR 10.63；95%CI，1.48至76.08）。氟西泮和蜜蜂花疗法与SB症状减轻的关联程度较低。：关于儿童SB治疗的数据有限。迫切需要开展设计合理、针对足够数量患者且基于标准化和完善诊断标准的未来研究。
