Harris L F, Buckle T F, Coffey F L
South Med J. 1986 Feb;79(2):193-6. doi: 10.1097/00007611-198602000-00014.
Intravenous antibiotics can be administered safely and effectively and at substantially less cost in a home environment. Patients who are candidates for this treatment must be in stable condition clinically, possess a ready venous access, and show the mental and physical capabilities required to administer intravenous medication. Antibiotics must be delivered promptly and retain their sterility and activity until infusion. Close monitoring of the patient during therapy is essential. Orthopedic infections, mainly osteomyelitis, septic arthritis, and bursitis, have thus far been our most frequently treated infections, with Staphylococcus aureus, aerobic gram-negative bacilli, and S epidermidis the most commonly encountered pathogens. Penicillins, cephalosporins and aminoglycosides have been given most often. Cure rates have exceeded 85%, and many patients resume usual activities during treatment. Complications are unusual, cost savings are substantial, and patient satisfaction is maximal.
静脉注射抗生素在家庭环境中能够安全、有效地给药，而且成本要低得多。适合这种治疗的患者临床病情必须稳定，要有现成的静脉通路，并且具备自行静脉给药所需的心理和身体能力。抗生素必须迅速给药，并在输注前保持无菌和活性。治疗期间对患者进行密切监测至关重要。骨科感染，主要是骨髓炎、化脓性关节炎和滑囊炎，是迄今为止我们治疗最频繁的感染，金黄色葡萄球菌、需氧革兰氏阴性杆菌和表皮葡萄球菌是最常见的病原体。青霉素、头孢菌素和氨基糖苷类药物使用最为频繁。治愈率超过85%，许多患者在治疗期间恢复了日常活动。并发症罕见，节省大量成本，患者满意度最高。
