Department of Cardiology, College of Medicine, Ewha Womans University, Seoul, South Korea.
Cardiovascular Devices Division, National Institute of Food and drug safety Evaluation, Cheongju-si, South Korea.
Sci Rep. 2019 Feb 26;9(1):2746. doi: 10.1038/s41598-019-38928-6.
We characterized the f-waves in atrial fibrillation (AF) in the surface ECG by quantifying the amplitude, irregularity, and dominant rate of the f-waves in leads II, aVL, and V, and investigated whether those parameters of the f-waves could discriminate long-standing persistent AF (LPeAF) from non-LPeAF. A total of 224 AF patients were enrolled: 112 with PAF (87 males), 48 with PeAF (38 males), and 64 with LPeAF (47 males). The f-waves in surface ECG leads V, aVL, and II, which reflect well electrical activity in the right atrium (RA), the left atrium (LA), and both atria, respectively, were analyzed. The f-waves for LPeAF had lower amplitudes in II and aVL, increased irregularity and a higher dominant rate in II and V compared to PAF and PeAF (all p < 0.02). In a multivariate analysis, a low amplitude in lead II (<34.6 uV) and high dominant rate in lead V (≧390/min) (p < 0.00) independently discriminated LPeAF from the other AF types. The f-waves combined with both a low amplitude in lead II and high dominant rate in lead V were significantly associated with LPeAF (OR 6.27, p < 0.001). Characteristics of the f-waves on the surface ECG could discriminate LPeAF from other types of AF.
我们通过量化心电图 II 导联、aVL 导联和 V 导联中 f 波的振幅、不规则性和主导频率，来对心房颤动（AF）中的 f 波进行特征描述，并研究这些 f 波参数是否可以区分持续性长程 AF（LPeAF）与非 LPeAF。共纳入 224 例 AF 患者：112 例为 PAF（87 例为男性），48 例为 PeAF（38 例为男性），64 例为 LPeAF（47 例为男性）。分析了体表心电图导联 V、aVL 和 II 中的 f 波，它们分别反映了右心房（RA）、左心房（LA）和双心房的电活动。与 PAF 和 PeAF 相比，LPeAF 的 f 波在 II 和 aVL 导联的振幅较低，在 II 和 V 导联的不规则性增加，主导频率较高（均 p<0.02）。在多变量分析中，II 导联的低振幅（<34.6 uV）和 V 导联的高主导频率（≧390/min）（p<0.00）独立区分了 LPeAF 与其他 AF 类型。f 波结合 II 导联的低振幅和 V 导联的高主导频率与 LPeAF 显著相关（OR 6.27，p<0.001）。体表心电图 f 波的特征可区分 LPeAF 与其他类型的 AF。
