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玻璃体内意外注射Ozurdex®治疗视网膜分支静脉阻塞:晶状体后囊完整及黄斑水肿消退

Accidental Intralenticular Injection of Ozurdex® for Branch Retinal Vein Occlusion: Intact Posterior Capsule and Resolution of Macular Edema.

作者信息

Kurt Ali, Durukan Ali Hakan, Küçükevcilioğlu Murat

机构信息

Ahi Evran University Faculty of Medicine, Department of Ophthalmology, Turkey.

Health Sciences University Faculty of Medicine, Department of Ophthalmology, Turkey.

出版信息

Case Rep Ophthalmol Med. 2019 Jan 23;2019:8630504. doi: 10.1155/2019/8630504. eCollection 2019.

DOI:10.1155/2019/8630504
PMID:30809404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6364128/
Abstract

PURPOSE

We present a case of accidental intralenticular injection of Ozurdex implant in a patient with macular edema secondary to branch retinal vein occlusion.

METHOD

A case report.

RESULTS

Intravitreal dexamethasone implant injection had been performed for macular edema due to left superior temporal vein branch occlusion to the left eye of a 78-year-old male patient. The slit-lamp examination 85 days later revealed that the dexamethasone implant was intralenticular. The best-corrected visual acuity (BCVA) was 0.16 on the Snellen chart. Cataract surgery was decided on for the cataract as there was no anterior chamber inflammation, the intraocular pressure (IOP) was normal, and the macular edema had resolved. Uneventful phacoemulsification within the bag intraocular lens placement was performed.

CONCLUSIONS

Accidental intralenticular Ozurdex injection is an extremely rare complication. The surgeon must decide whether to continue to observe or intervene immediately when such a complication is encountered. Cataract surgery can be planned if the macular edema has resolved and a cataract has developed. It is important to evaluate the posterior capsule with ultrasound biomicroscopy and Scheimpflug imaging before the cataract surgery to ensure a safe surgical procedure.

摘要

目的

我们报告一例视网膜分支静脉阻塞继发黄斑水肿患者意外晶状体内注射Ozurdex植入物的病例。

方法

病例报告。

结果

对一名78岁男性患者的左眼因左上颞静脉分支阻塞引起的黄斑水肿进行了玻璃体内地塞米松植入物注射。85天后裂隙灯检查发现地塞米松植入物位于晶状体内部。Snellen视力表测得的最佳矫正视力(BCVA)为0.16。由于无前房炎症、眼压(IOP)正常且黄斑水肿已消退,决定对白内障进行手术。在囊袋内顺利进行了超声乳化人工晶状体植入术。

结论

意外晶状体内注射Ozurdex是一种极其罕见的并发症。遇到这种并发症时,外科医生必须决定是继续观察还是立即干预。如果黄斑水肿已消退且出现白内障,则可计划进行白内障手术。白内障手术前用超声生物显微镜和Scheimpflug成像评估后囊膜很重要,以确保手术安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec8/6364128/7350df355f36/CRIOPM2019-8630504.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec8/6364128/e2b5519ea7f2/CRIOPM2019-8630504.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec8/6364128/8566ea153972/CRIOPM2019-8630504.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec8/6364128/7350df355f36/CRIOPM2019-8630504.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec8/6364128/e2b5519ea7f2/CRIOPM2019-8630504.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec8/6364128/8566ea153972/CRIOPM2019-8630504.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec8/6364128/7350df355f36/CRIOPM2019-8630504.003.jpg

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本文引用的文献

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Am J Ophthalmol Case Rep. 2016 Aug 11;4:38-40. doi: 10.1016/j.ajoc.2016.08.001. eCollection 2016 Dec.
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玻璃体内注射地塞米松治疗黄斑水肿和葡萄膜炎:一项全面的叙述性综述
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Iatrogenic crystalline lens injury during intravitreal injection of triamcinolone acetonide: A report of two cases.玻璃体内注射曲安奈德期间发生的医源性晶状体损伤:2例报告
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Immortal Ozurdex: A 10-month follow-up of an intralenticular implant.长效奥助得:晶状体囊内植入物的10个月随访
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