Lee Won Gu
Department of Neurology, Kosin University College of Medicine, Busan, Korea.
J Epilepsy Res. 2018 Dec 31;8(2):100-104. doi: 10.14581/jer.18018. eCollection 2018 Dec.
Carbon monoxide (CO) poisoning is one of the most serious medical emergencies causing life-threatening conditions, including cardiovascular and neurological sequelae. Acute CO poisoning can lead to myocardial ischemia, ventricular arrhythmia, syncope, seizures, and coma. Seizures and other neurological complications in the early stages of presentation are related to severe intoxication in CO poisoning. In such situations, aggressive hyperbaric oxygen therapy is recommended. In CO poisoning, non-convulsive status epilepticus has rarely been observed following hyperbaric oxygen therapy (HBO). We report a case of CO poisoning presenting as non-convulsive status epilepticus treated with HBO. Mechanisms and implications for non-convulsive status epilepticus provocation during HBO treatment are discussed.
一氧化碳(CO)中毒是最严重的医疗紧急情况之一,可导致危及生命的状况,包括心血管和神经后遗症。急性CO中毒可导致心肌缺血、室性心律失常、晕厥、癫痫发作和昏迷。发病早期的癫痫发作和其他神经并发症与CO中毒的严重中毒有关。在这种情况下,建议进行积极的高压氧治疗。在CO中毒中,高压氧治疗(HBO)后很少观察到非惊厥性癫痫持续状态。我们报告一例以非惊厥性癫痫持续状态为表现的CO中毒患者接受了HBO治疗。文中讨论了HBO治疗期间引发非惊厥性癫痫持续状态的机制及影响。