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高压氧治疗诱发的部分性癫痫发作:可能机制及意义

Partial seizure provoked by hyperbaric oxygen therapy: possible mechanisms and implications.

作者信息

Doherty Michael J, Hampson Neil B

机构信息

Swedish Epilepsy Center, Virginia Mason Medical Center, Seattle, Washington 98122, USA.

出版信息

Epilepsia. 2005 Jun;46(6):974-6. doi: 10.1111/j.1528-1167.2005.69804.x.

DOI:10.1111/j.1528-1167.2005.69804.x
PMID:15946345
Abstract

Hyperbaric oxygen treatment (HBO2) is used commonly for treatment of bone and soft-tissue radiation necrosis. It may be a potential therapy for radiation necrosis seen after brain irradiation. HBO2 risks include generalized tonic-clonic convulsions. We report a patient after resection of anaplastic astrocytoma and 5,580 cGy of total external-beam radiation treatments with brain radiation necrosis who underwent HBO2 therapy and developed a partial seizure during treatment. Mechanisms and implications are discussed.

摘要

高压氧治疗(HBO2)常用于治疗骨和软组织放射性坏死。它可能是脑照射后出现的放射性坏死的一种潜在治疗方法。HBO2的风险包括全身性强直阵挛性惊厥。我们报告了一名间变性星形细胞瘤切除术后接受5580 cGy全脑外照射治疗后发生脑放射性坏死的患者,该患者接受了HBO2治疗,并在治疗期间出现了部分性癫痫发作。本文讨论了其机制及影响。

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