Lashner B A, Kirsner J B, Hanauer S B
Gastroenterology. 1986 Apr;90(4):1039-41. doi: 10.1016/0016-5085(86)90884-x.
A 17-yr-old boy with Crohn's disease and growth retardation developed an acute abdominal crisis while receiving total parenteral nutritional support. Acute pancreatitis was confirmed surgically. After recovery, in an attempt to provide adequate calories and to elucidate the inciting agent, he was rechallenged with his original total parenteral nutritional solution which contained 500 ml/day of a 20% fat emulsion. Symptoms and signs of acute pancreatitis quickly returned. Total parenteral nutrition was continued without the fat emulsion and symptoms and signs disappeared. This case suggests that acute pancreatitis was due to intolerance of high-concentration lipid emulsion.
一名患有克罗恩病并伴有生长发育迟缓的17岁男孩在接受全胃肠外营养支持时发生了急性腹部危象。经手术确诊为急性胰腺炎。康复后，为了提供足够的热量并找出致病因素，给他重新输注了原来的全胃肠外营养溶液，该溶液每天含有500毫升20%的脂肪乳剂。急性胰腺炎的症状和体征迅速再次出现。继续进行不含脂肪乳剂的全胃肠外营养，症状和体征消失。该病例提示急性胰腺炎是由于对高浓度脂质乳剂不耐受所致。
