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A Lower Dose of Efavirenz Can Be Coadministered With Rifampicin and Isoniazid in Tuberculosis Patients.

作者信息

Kaboggoza Julian P, Wang Xinxhu, Neary Megan, Ayuso Pedro, Sekaggya-Wiltshire Christine, Nakalema Shadia, Owen Andrew, McClure Myra, Lamorde Mohammed, Boffito Marta

机构信息

Infectious Diseases Institute, Makerere University College of Health Sciences, Mulago Hospital Complex, Kampala, Uganda.

Jeffriess Research Trust Laboratories, Department of Medicine, Imperial College, London, United Kingdom.

出版信息

Open Forum Infect Dis. 2019 Jan 16;6(2):ofz035. doi: 10.1093/ofid/ofz035. eCollection 2019 Feb.

DOI:10.1093/ofid/ofz035
PMID:30815503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6386798/
Abstract
摘要

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本文引用的文献

1
Pharmacokinetics of Efavirenz 400 mg Once Daily Coadministered With Isoniazid and Rifampicin in Human Immunodeficiency Virus-Infected Individuals.依非韦伦 400 毫克每日一次与异烟肼和利福平联合用于人类免疫缺陷病毒感染个体的药代动力学。
Clin Infect Dis. 2019 Jan 18;68(3):446-452. doi: 10.1093/cid/ciy491.
2
Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naïve HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study.初治HIV感染患者每日一次服用400毫克和600毫克依非韦伦96周的综合药代动力学、药效学和药物遗传学评估：ENCORE1研究结果
Clin Pharmacokinet. 2016 Jul;55(7):861-873. doi: 10.1007/s40262-015-0360-5.
3
Efficacy of 400 mg efavirenz versus standard 600 mg dose in HIV-infected, antiretroviral-naive adults (ENCORE1): a randomised, double-blind, placebo-controlled, non-inferiority trial.在未接受过抗逆转录病毒治疗的 HIV 感染成人中，400 毫克依非韦伦与标准 600 毫克剂量的疗效比较（ENCORE1）：一项随机、双盲、安慰剂对照、非劣效性试验。
Lancet. 2014 Apr 26;383(9927):1474-1482. doi: 10.1016/S0140-6736(13)62187-X. Epub 2014 Feb 10.