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《加拿大偏头痛患者的生存状况:一项全国性社区研究》。

Living with Migraine in Canada - A National Community-Based Study.

机构信息

From the Department of Clinical Neurosciences and Hotchkiss Brain Institute,University of Calgary,Calgary, Alberta,Canada.

Department of Community Health Sciences and O'Brien Institute for Public Health,University of Calgary,Calgary, Alberta,Canada.

出版信息

Can J Neurol Sci. 2019 Mar;46(2):216-223. doi: 10.1017/cjn.2019.3. Epub 2019 Feb 28.

DOI:10.1017/cjn.2019.3
PMID:30816083
Abstract

OBJECTIVE

To develop a detailed profile of individuals living with migraine in Canada. Such a profile is important for planning and administration of services.

METHODS

The 2011-2012 Survey of Living with Neurological Conditions in Canada (SLNCC), a cross-sectional community-based survey, was used to examine a representative sample of migraineurs (N = 949) aged 15 years and older. Several health-related variables were examined (e.g., general health, health utility index (HUI) [a measure of health status and health-related quality of life, where dead = 0.00 and perfect health = 1.00], stigma, depression, and social support). Respondents were further stratified by sex, age, and age of migraine onset. Weighted overall and stratified prevalence estimates and odds ratios, both with 95% CIs, were used to estimate associations.

RESULTS

Overall, males had poorer health status compared with females (e.g., mean HUI was 0.67 in males vs. 0.82 in females; men had over two times the odds of their migraine limiting educational and job opportunities compared with females). Poorer health-related variables were seen in the older age groups (35-64 years/≥65 years) compared with the 15-34-year age group. There were no differences between those whose migraine symptoms began before versus after the age of 20 years.

CONCLUSIONS

In this Canadian sample, migraine was associated with worse health-related variables in men compared with women. However, both men and women were significantly affected by migraine across various health-related variables. Thus, it is important to improve clinical and public health interventions addressing the impact of migraine across individuals of all ages, sexes, and sociodemographic backgrounds.

摘要

目的

描绘加拿大偏头痛患者的详细特征。此类特征对于规划和管理服务十分重要。

方法

采用 2011-2012 年加拿大神经系统疾病生存状况调查(SLNCC),这是一项基于社区的横断面调查,对年龄在 15 岁及以上的偏头痛患者(N=949)进行了代表性样本分析。调查了多项健康相关变量(例如,一般健康状况、健康效用指数(HUI)[一种衡量健康状况和健康相关生活质量的指标,死亡=0.00,完全健康=1.00]、耻辱感、抑郁和社会支持)。进一步按性别、年龄和偏头痛发病年龄对受访者进行分层。使用加权总体和分层患病率估计值和比值比(95%CI)来估计关联。

结果

总体而言,男性的健康状况比女性差(例如,男性的平均 HUI 为 0.67,女性为 0.82;与女性相比,男性偏头痛限制受教育和工作机会的几率高出两倍)。与 15-34 岁年龄组相比,年龄较大的组(35-64 岁/≥65 岁)的健康相关变量更差。偏头痛症状在 20 岁之前或之后开始的人群之间没有差异。

结论

在加拿大的这一样本中,与女性相比,偏头痛与男性的健康相关变量更差有关。然而,无论男性还是女性,在各种健康相关变量方面都受到偏头痛的显著影响。因此,重要的是要改善针对所有年龄段、性别和社会人口背景的个体的偏头痛影响的临床和公共卫生干预措施。

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