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人类顶体的牛磺酸含量及氨基酸组成

Taurine content and amino acid composition of human acrosome.

作者信息

Velázquez A, Delgado N M, Rosado A

出版信息

Life Sci. 1986 Mar 17;38(11):991-5. doi: 10.1016/0024-3205(86)90232-8.

Abstract

The presence and concentration of taurine was determined by amino acid analysis in human spermatozoa acrosomes isolated by the method of Srivastava. Taurine is one of the four amino acids whose concentration is higher in the acrosomal extracts, being only lower than histidine, methionine and lysine. It is worth mentioning that these four amino acids constituted 50% the free amino acid concentration in this organelle. The role that this high concentration of taurine, and also the presence of considerable amounts of methyl histidine may have in the functioning of the acrosome, is discussed.

摘要

采用Srivastava方法分离出人类精子顶体,通过氨基酸分析测定其中牛磺酸的存在及浓度。牛磺酸是顶体提取物中浓度较高的四种氨基酸之一,仅低于组氨酸、蛋氨酸和赖氨酸。值得一提的是,这四种氨基酸占该细胞器中游离氨基酸浓度的50%。文中讨论了高浓度牛磺酸以及大量甲基组氨酸的存在可能对顶体功能产生的作用。

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