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经动脉化疗栓塞术治疗肝细胞癌:美国单中心初步经验

Balloon-Occluded Transarterial Chemoembolization for the Treatment of Hepatocellular Carcinoma: A Single-Center US Preliminary Experience.

作者信息

Goldman Daryl T, Singh Manu, Patel Rahul S, Nowakowski F Scott, Bishay Vivian, Ranade Mona, Lookstein Robert A, Fischman Aaron M

机构信息

Division of Interventional Radiology, Icahn School of Medicine at Mount Sinai, 1184 Fifth Ave., MC Level, New York, NY 10029.

Department of Radiology, Santa Barbara Cottage Hospital, Santa Barbara, California.

出版信息

J Vasc Interv Radiol. 2019 Mar;30(3):342-346. doi: 10.1016/j.jvir.2018.11.026.

Abstract

This report describes a single-center experience with balloon-occluded transarterial chemoembolization for liver-directed therapy. A total of 26 patients (11 male, 4 female; mean age, 65 y ± 7) with 28 tumors (mean diameter, 2.7 cm; range, 1.1-5.9 cm) were treated. Technical success rate was 100% (28 of 28 cases), with 1 minor complication of left portal vein thrombosis and small liver infarct. Of the 15 tumors analyzed for response, 60% (9 of 15) exhibited complete response, 33.3% (5 of 15) exhibited partial response, and 6.6% (1 of 15) had stable disease on follow-up. Eight patients exhibited overall progression with a new hepatic lesion and a median time to progression of 7.9 months (range, 5-11 mo).

摘要

本报告描述了单中心采用球囊闭塞经动脉化疗栓塞术进行肝靶向治疗的经验。共治疗了26例患者(11例男性,4例女性;平均年龄65岁±7岁),有28个肿瘤(平均直径2.7 cm;范围1.1 - 5.9 cm)。技术成功率为100%(28例中的28例),有1例轻微并发症,为左门静脉血栓形成和小面积肝梗死。在分析反应的15个肿瘤中,60%(15个中的9个)表现为完全缓解,33.3%(15个中的5个)表现为部分缓解,6.6%(15个中的1个)在随访中病情稳定。8例患者出现新的肝脏病变,总体病情进展,进展的中位时间为7.9个月(范围5 - 11个月)。

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