Menzel K, Buchenau W, Artjuschenko T, Nissel C, Heitsch J
Zentralbl Gynakol. 1986;108(1):44-53.
The adaption of the cardiovascular system to hypoxia has been examined in piglets aged 3 to 81 hour. The reaction of the piglets to a shorttime normobaric hypoxia was very different: In 50% there was an inadequate reaction with decrease of blood pressure, heart rate, pulse pressure and therefore of stroke volume, in 30% there was in compliance with the adult mechanism a compensatory increase of blood pressure, heart rate, pulse pressure and stroke volume. Only in 2 cases a compensatory increase of blood pressure could be observed in combination with a simultaneous decrease of heart rate. The results refer once more to the fact, that the reactions of the cardiovascular system of the neonate to hypoxia can be very variable and require an individual therapeutic regime provided that they are transferable to the human newborn and premature baby.
对3至81小时龄的仔猪的心血管系统对缺氧的适应性进行了研究。仔猪对短时间常压缺氧的反应差异很大：50%的仔猪反应不足，表现为血压、心率、脉压下降，进而心输出量减少；30%的仔猪符合成年机制，血压、心率、脉压和心输出量出现代偿性增加。仅在2例中观察到血压代偿性增加同时心率下降。这些结果再次表明，新生儿心血管系统对缺氧的反应可能非常多变，并且如果这些反应适用于人类新生儿和早产儿，则需要个体化的治疗方案。
