Lou Alina Y, Wannemuehler Todd J, Russell Paul T, Barahimi Behin, Sobel Rachel K
Vanderbilt University Medical Center, Nashville, TN, USA.
Orbit. 2020 Feb;39(1):64-67. doi: 10.1080/01676830.2019.1582071. Epub 2019 Mar 1.
Orbital apex syndrome as a result of invasive fungal sinusitis is a disease entity most commonly found in immunocompromised patients. Infectious invasion affecting the orbital apex can have devastating visual and life-threatening consequences. and species are the most common causes of such infections. fungal sinusitis is a known entity, but its ability to cause an orbital apex syndrome has not yet been reported. Here, we present a case of orbital apex syndrome in an immunocompromised patient with invasive fungal sinusitis caused by species. The patient underwent sinus washout and placement of an intraorbital catheter for local instillation of amphotericin B for 10 days, in addition to systemic antifungal treatment, with clinical resolution of infection. The use of an intraorbital catheter for local treatment of fungal infection may offer an exenteration-sparing treatment option in these patients.
侵袭性真菌性鼻窦炎导致的眶尖综合征是一种在免疫功能低下患者中最常见的疾病实体。影响眶尖的感染性侵袭可导致严重的视力损害和危及生命的后果。 和 是此类感染最常见的病因。真菌性鼻窦炎是一种已知疾病，但其导致眶尖综合征的能力尚未见报道。在此，我们报告一例免疫功能低下患者因 种真菌引起侵袭性真菌性鼻窦炎导致眶尖综合征的病例。除全身抗真菌治疗外，患者接受了鼻窦冲洗，并放置眶内导管局部滴注两性霉素B 10天，感染临床治愈。使用眶内导管局部治疗真菌感染可能为这些患者提供一种避免眶内容摘除术的治疗选择。
