支气管镜检查的血流动力学效应。芬太尼和阿芬太尼预处理的效果。
The haemodynamic effects of bronchoscopy. Effect of pretreatment with fentanyl and alfentanil.
作者信息
Wark K J, Lyons J, Feneck R O
出版信息
Anaesthesia. 1986 Feb;41(2):162-7. doi: 10.1111/j.1365-2044.1986.tb13173.x.
The cardiovascular responses to bronchoscopy under general anaesthesia were investigated in 36 premedicated patients. Twelve patients acting as controls received a standard intravenous anaesthetic of intermittent thiopentone and suxamethonium. A further 24 patients were given either fentanyl 6 micrograms/kg or alfentanil 18 micrograms/kg intravenously, one minute prior to induction. There were significant rises in systolic arterial blood pressure (p less than 0.05) and in rate pressure product (p less than 0.05) in the patients in the control group, but these changes were not seen in those patients receiving either fentanyl or alfentanil. However, dysrhythmias and ST segment changes indicative of myocardial ischaemia were present in some patients in all three groups.
对36例已进行术前用药的患者在全身麻醉下进行支气管镜检查时的心血管反应进行了研究。12例作为对照的患者接受了硫喷妥钠和琥珀酰胆碱间歇性静脉注射的标准麻醉剂。另外24例患者在诱导前1分钟静脉注射6微克/千克芬太尼或18微克/千克阿芬太尼。对照组患者的收缩动脉血压（p<0.05）和心率血压乘积（p<0.05）显著升高，但在接受芬太尼或阿芬太尼的患者中未观察到这些变化。然而，三组中的一些患者均出现了心律失常和提示心肌缺血的ST段改变。
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