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VirtualDose-IR:一款用于介入放射学中报告器官剂量的基于云的软件。

VirtualDose-IR: a cloud-based software for reporting organ doses in interventional radiology.

机构信息

School of Physical Sciences, University of Science and Technology of China, Hefei, China.

出版信息

Phys Med Biol. 2019 Apr 26;64(9):095012. doi: 10.1088/1361-6560/ab0bd5.

Abstract

A cloud-based software, VirtualDose-IR (Virtual Phantoms Inc., Albany, New York, USA), designed to report organ doses and effective doses for a diverse patient population from interventional radiology (IR) procedures has been developed and tested. This software is based on a comprehensive database of Monte Carlo-generated organ dose built with a set of 21 anatomically realistic patient phantoms. The patient types included in this database are both male and female people with different ages reflecting reference adults, obese people with different BMIs and pregnant women at different gestational stages. Selectable parameters such as patient type, tube voltage, filtration thickness, beam direction, field size, and irradiation site are also considered in VirtualDose-IR. The software has been implemented using the 'Software as a Service (SaaS)' delivery concept permitting simultaneous multi-user, multi-platform access without requiring local installation. The patient doses resulting from different target sites and patient populations were reported using the VirtualDose-IR system. The patient doses under different source to surface distances (SSD) and beam angles calculated by VirtualDose-IR and Monte Carlo simulations were compared. For most organs, the dose differences between VirtualDose-IR results and Monte Carlo results were less than 0.3 mGy at 15 000 mGy * cm kerma-area product (KAP). The organ dose results were compared with measurement data previously reported in literatures. The doses to organs that were located within the irradiation field match closely with experimental measurement data. The differences in the effective dose values between calculated using VirtualDose-IR and those measured were less than 2.5%. The dose errors of most organs between VirtualDose-IR and literature results were less than 40%. These results validate the accuracy of organ doses reported by VirtualDose-IR. With the inclusion of pre-specified clinical IR examination parameters (such as beam direction, target location, field of view and beam quality) and the latest anatomically realistic patient phantoms in Monte Carlo simulations, VirtualDose-IR provides users with accurate dose information in order to systematically compare, evaluate, and optimize IR plans.

摘要

一款名为 VirtualDose-IR 的基于云的软件已经开发并测试完成,该软件旨在为介入放射学 (IR) 程序中的不同患者人群报告器官剂量和有效剂量。该软件基于一个使用一组 21 个解剖学逼真的人体模型生成的器官剂量的综合蒙特卡罗数据库。该数据库中包含的患者类型包括不同年龄的男性和女性,反映了参考成年人、不同 BMI 的肥胖者和不同妊娠阶段的孕妇。VirtualDose-IR 还考虑了可选参数,如患者类型、管电压、过滤厚度、射束方向、射野大小和照射部位。该软件采用“软件即服务 (SaaS)”交付概念实现,允许同时多用户、多平台访问,无需本地安装。使用 VirtualDose-IR 系统报告了来自不同靶位和患者人群的患者剂量。比较了 VirtualDose-IR 和蒙特卡罗模拟计算的不同源皮距 (SSD) 和射束角度下的患者剂量。对于大多数器官,在 15000 mGy * cm 比释动能面积乘积 (KAP) 下,VirtualDose-IR 结果和蒙特卡罗结果之间的剂量差异小于 0.3 mGy。将器官剂量结果与文献中先前报道的测量数据进行比较。照射野内器官的剂量与实验测量数据非常吻合。使用 VirtualDose-IR 计算的有效剂量值与测量值之间的差异小于 2.5%。VirtualDose-IR 和文献结果之间的大多数器官的有效剂量值差异小于 40%。这些结果验证了 VirtualDose-IR 报告的器官剂量的准确性。通过包括预设的临床 IR 检查参数(如射束方向、靶位、视野和射束质量)和最新的蒙特卡罗模拟解剖学逼真的人体模型,VirtualDose-IR 为用户提供了准确的剂量信息,以便系统地比较、评估和优化 IR 计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80a6/7480071/6bc9b810985e/nihms-1619619-f0001.jpg

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