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腹腔镜双侧性腺切除术及使用补片修补腹股沟疝治疗完全性雄激素不敏感综合征:一例报告

Laparoscopic Bilateral Gonadectomy and Inguinal Hernia Repair with Mesh for Complete Androgen Insensitivity Syndrome: A Case Report.

作者信息

Dellaportas Dionysios, Chatzipapas Ioannis, Pandraklakis Anastasios, Michala Lina

机构信息

2nd Department of Surgery, Aretaieion University Hospital, National and Kapodistrian University of Athens, Athens, Greece.

1st Department of Obstetrics and Gynecology, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

J Pediatr Adolesc Gynecol. 2019 Aug;32(4):443-445. doi: 10.1016/j.jpag.2019.02.123. Epub 2019 Feb 27.

Abstract

BACKGROUND

Complete androgen insensitivity (CAIS) is a difference of sex development, in which there is complete androgen receptor resistance, leading to a female phenotype, despite the presence of normal testes. There is a recognized risk of testicular germ cell tumor in adulthood as high as 15%, and gonadectomy is usually performed in late adolescence or early adulthood.

CASE

A 20-year-old patient, with a known diagnosis of CAIS since the age of 16, underwent magnetic resonance imaging of the pelvis, which revealed the testes lying deep into the inguinal canal. The patient was explored laparoscopically and using the technique of transabdominal preperitoneal hernia repair both testes were successfully reduced into the peritoneal cavity and resected. In addition, the defect of the internal inguinal ring was covered and reinforced using a prosthetic polypropylene mesh.

SUMMARY AND CONCLUSION

Minimally invasive gonadectomy is feasible even for gonads situated deep into the inguinal canal. Established benefits of laparoscopic surgery such as reduced postoperative pain, rapid recovery, aesthetically small incisions, and early return to normal activities are very important for CAIS patients. Multidisciplinary team work, among gynecologists and general surgeons, provides excellent results in these complex cases.

摘要

背景

完全雄激素不敏感综合征(CAIS)是一种性发育差异疾病,其中存在完全的雄激素受体抵抗,导致尽管存在正常睾丸,但仍表现为女性表型。成年后发生睾丸生殖细胞肿瘤的公认风险高达15%,性腺切除术通常在青春期后期或成年早期进行。

病例

一名20岁患者,自16岁起就被诊断为CAIS,接受了骨盆磁共振成像检查,结果显示睾丸位于腹股沟管深部。对该患者进行了腹腔镜探查,并采用经腹腹膜前疝修补技术,成功将双侧睾丸回纳至腹腔并切除。此外,使用聚丙烯人工补片覆盖并加强腹股沟内环缺损。

总结与结论

即使对于位于腹股沟管深部的性腺,微创性腺切除术也是可行的。腹腔镜手术的既定益处,如术后疼痛减轻、恢复快、切口美观小以及能早期恢复正常活动,对CAIS患者非常重要。妇科医生和普通外科医生之间的多学科团队协作,在这些复杂病例中能取得出色的治疗效果。

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