Miller G W, Josey A F
South Med J. 1978 Sep;71(9):1062-4.
Brain stem evoked response (BER) audiometry presents abnormal findings in patients with acoustic neuromas. The test involves averaging of recordings at the vertex as sound-triggered nerve impulses travel from the cochlea to the brain stem. From the time the sound stimulus arrives at the cochlea until it reaches the first major brain stem synapse (within 10 milliseconds), five major waves have been identified as typical of normal averaged responses. Abnormality in the cochlea or eighth nerve causes specific changes in pattern, primarily in wave latency. These latency shifts can be used to predict the site of the lesion. In evaluating 17 lesions of the cerebellopontine angle, BER audiometry was accurate in the diagnosis of all of the tumors. This diagnostic tool should play a prominent role when acoustic tumor is suspected.
脑干诱发电位(BER)听力测定在听神经瘤患者中呈现异常结果。该测试涉及在头顶对记录进行平均处理,因为声音触发的神经冲动从耳蜗传导至脑干。从声音刺激到达耳蜗直至其抵达第一个主要的脑干突触(在10毫秒内),已识别出五个主要波,它们是正常平均反应的典型特征。耳蜗或第八对脑神经的异常会导致波形的特定变化,主要是波潜伏期的变化。这些潜伏期变化可用于预测病变部位。在评估17例桥小脑角病变时,BER听力测定对所有肿瘤的诊断都是准确的。当怀疑患有听神经瘤时,这种诊断工具应发挥重要作用。