Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Department of Anatomical Pathology, The Ottawa Hospital, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Placenta. 2019 Feb;77:46-57. doi: 10.1016/j.placenta.2019.01.009. Epub 2019 Jan 11.
Placental pathology is a key modality for determining placental health during pregnancy, especially in the event of adverse pregnancy outcomes. However, issues with standardization in placental diagnosis, reporting practices and clinical translation prevent this modality from being used to its full potential. This article will highlight these standardization issues and summarize ongoing work in this field to overcome them. Additionally, we propose a synoptic reporting framework for placental pathology based on current consensus guidelines, aimed at enhancing the comprehensiveness and quality of reporting placental findings. We believe this approach will improve our understanding of the placenta in adverse pregnancy outcomes and, importantly, offer the opportunity to increase knowledge translation to key stakeholder groups including patients.
胎盘病理学是确定妊娠期间胎盘健康的关键手段,尤其是在出现不良妊娠结局的情况下。然而,胎盘诊断、报告实践和临床转化方面的标准化问题限制了该手段的充分发挥。本文将重点介绍这些标准化问题,并总结该领域正在开展的工作,以克服这些问题。此外,我们还基于当前的共识指南,提出了胎盘病理学的综合报告框架,旨在提高胎盘报告的全面性和质量。我们相信,这种方法将有助于提高我们对不良妊娠结局中胎盘的认识,重要的是,为包括患者在内的关键利益相关者群体提供增加知识转化的机会。