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下一代测序技术在血液系统疾病中的应用——印度现状:ISHBT 2018年最新进展

Applications of Next Generation Sequencing in Haematological Disorders-Indian Status: Updates from ISHBT 2018.

作者信息

Maddali Madhavi, Balasubramanian Poonkuzhali

机构信息

Department of Haematology, Christian Medical College and Hospital, Vellore, 632004 India.

出版信息

Indian J Hematol Blood Transfus. 2019 Jan;35(1):17-21. doi: 10.1007/s12288-018-01068-4. Epub 2019 Jan 17.

Abstract

Research in India based on next generation sequencing (NGS) has been plentiful over the past few years. Significant progress in research both in benign and malignant haematology can be attributed to this technique. It has now progressed to both diagnostic and a theranostic modality in many areas of not only haematology but also other medical specialities. Papers presented at the annual conference of the Indian Society of Haematology and Blood Transfusion, ISHBT (Haematocon 2018) highlighted a snapshot of the research activities using NGS that are ongoing in various academic and other centres. This review summarizes the salient findings of the original research abstracts presented. The papers are divided into two broad subsections of non-malignant and malignant haematology.

摘要

在过去几年里,印度基于下一代测序(NGS)的研究成果丰硕。良性和恶性血液学研究取得的重大进展都可归功于这项技术。如今,它不仅在血液学的许多领域,而且在其他医学专科领域,都已发展成为一种诊断和治疗诊断手段。在印度血液学与输血学会(ISHBT)年度会议(2018年血液学大会)上发表的论文,展示了在各个学术中心和其他机构正在进行的使用NGS的研究活动的概况。本综述总结了所发表的原始研究摘要的主要发现。这些论文分为非恶性血液学和恶性血液学两个主要部分。

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