Redkar Rajeev Gurunath, Raj Vinod, Bangar Anant, Hathiramani Varun, Chigicherla Swathi, Tewari Shruti
Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India.
Department of Pediatric Surgery, Kings College Hospital, NHS Foundation Trust, London, UK.
Afr J Paediatr Surg. 2018 Jan-Mar;15(1):31-35. doi: 10.4103/ajps.AJPS_99_17.
Chronic refractory constipation (CRC) is an uncommon type of constipation. These children have persistent symptoms even after treatment with high dose laxatives, which may cause abdominal distension, vomiting, cramping and bloating. We conducted this study to assess the diagnostic and therapeutic role of anorectal myomectomy in children with CRC.
This study includes 107 patients who fit the criteria of CRC. Complete bowel preparation with polyethylene glycol solution, enemas and antibiotics was carried out before surgery in all patients. The anorectal myomectomy was carried out under general anaesthesia with the patient in the high lithotomy position. The patients were followed up from 6 months to 13 years postoperatively. The success of myomectomy was based on the daily and complete passage of stools without the need for medication or enemas.
A total of 99 patients were included in the study, of which, 86 (86.86%) patients showed a good response to anorectal myomectomy. Of these, 32 patients had normal histology, 14 had histology suggestive of Hirschsprung's disease, 8 had hypoganglionosis, 10 had ultra-short segment Hirschsprung's disease and 22 had hypertrophic nerves with immature ganglia. Poor response was seen in 13 (13.13%) patients of whom 5 had normal histology, 5 had Hirschsprung's disease, 2 had hypoganglionosis and 1 had ultra-short segment Hirschsprung's disease.
Anorectal myomectomy is an effective and technically simple procedure in selected patients with CRC for both diagnostic and therapeutic purposes.
慢性难治性便秘(CRC)是一种罕见的便秘类型。这些儿童即使在使用高剂量泻药治疗后仍有持续症状,这可能会导致腹胀、呕吐、绞痛和腹部胀气。我们开展这项研究以评估肛门直肠肌瘤切除术在CRC患儿中的诊断和治疗作用。
本研究纳入了107例符合CRC标准的患者。所有患者在手术前均用聚乙二醇溶液、灌肠剂和抗生素进行了充分的肠道准备。肛门直肠肌瘤切除术在全身麻醉下进行,患者取高截石位。对患者进行了术后6个月至13年的随访。肌瘤切除术的成功基于每日大便通畅且无需药物或灌肠。
共有99例患者纳入研究,其中86例(86.86%)患者对肛门直肠肌瘤切除术反应良好。其中,32例组织学正常,14例组织学提示先天性巨结肠,8例神经节减少症,10例超短段先天性巨结肠,22例神经肥厚伴神经节未成熟。13例(13.13%)患者反应不佳,其中5例组织学正常,5例先天性巨结肠,2例神经节减少症,1例超短段先天性巨结肠。
对于选定的CRC患者,肛门直肠肌瘤切除术在诊断和治疗方面都是一种有效且技术简单的手术。