Karampelias Vassileios, Koukouras Dimitrios, Tzorakoleftherakis Evaggelos, Mariolis-Sapsakos Theodoros, Chrysikos Dimosthenis
School of Medicine, University of Patras, Patras, Greece.
Department of 1st Propaedeutic Surgery, University of Athens, Medical School, Hippokratio Hospital, Athens, Greece.
Breast Dis. 2019;38(1):1-5. doi: 10.3233/BD-180355.
The mainstream treatment of breast cancer is radical mastectomy accompanied with Axillary Lymph Node Dissection (ALND). Lately, more conservative methods accompanied by adjuvant radiotherapy have been gradually replacing radical modalities. The Sentinel Lymph Node Biopsy (SLNB) has been considered such a valuable alternative to surgery conservative approach.
To assess the agreement between SLNB in breast cancer patients and pathology results following ALND and to provide correlation between the sentinel lymph nodes (SLN) anatomical topography and biopsy positivity according to SLNBs.
Two hundred female breast cancer patients (31 to 83 years of age) underwent partial or simple mastectomy with or without subsequent ALND. All patients were randomized against selection criteria and underwent SLNB.
In a set of 200 patients, 96.3% presented identical results between SLNB and pathology. 36% of them were confirmed with positive SLN through both approaches. Regarding the SLN topographic anatomical position, 67.3% of samples were located in the front axillary position, 24.5% in the front thoracic position, whereas 6.1% was located in the central axillary position.
The correlation between the SLN topographic anatomical position and the pathology results, revealed that the majority of the SLN accumulates in the front axillary region. A larger patient population will statistically support this association.
乳腺癌的主流治疗方法是根治性乳房切除术并伴有腋窝淋巴结清扫术（ALND）。最近，更保守的方法并辅以辅助放疗已逐渐取代根治性术式。前哨淋巴结活检（SLNB）已被认为是手术保守方法的一种有价值的替代方法。
评估乳腺癌患者SLNB与ALND后病理结果之间的一致性，并根据SLNB提供前哨淋巴结（SLN）解剖位置与活检阳性之间的相关性。
200名女性乳腺癌患者（年龄31至83岁）接受了部分或单纯乳房切除术，术后是否进行ALND。所有患者均根据选择标准随机分组并接受SLNB。
在一组200例患者中，96.3%的SLNB与病理结果一致。其中36%通过两种方法均证实SLN为阳性。关于SLN的地形解剖位置，67.3%的样本位于腋窝前部，24.5%位于胸前部，而6.1%位于腋窝中部。
SLN地形解剖位置与病理结果之间的相关性表明，大多数SLN聚集在腋窝前部区域。更大的患者群体将在统计学上支持这种关联。
