Marchenko A N, Sorokin E L, Pashentcev Ya E
Khabarovsk branch of S. Fyodorov Eye Microsurgery Federal State Institution, 211 Tikhookeanskaia St., Khabarovsk, Russian Federation, 680033.
Khabarovsk branch of S. Fyodorov Eye Microsurgery Federal State Institution, 211 Tikhookeanskaia St., Khabarovsk, Russian Federation, 680033; Far-Eastern State Medical University, 35 Muravyov-Amursky St., Khabarovsk, Russian Federation, 680000.
Vestn Oftalmol. 2019;135(1):47-52. doi: 10.17116/oftalma201913501147.
One of the most severe urgent conditions of the eye capable of leading to untreatable blindness is an acute attack of glaucoma. This condition is an acute decompensation of eye hydrodynamics, which develops with primary angle-closure glaucoma (PACG). Detectability of PACG is only high at the sudden development of an acute attack, which can cause a sharp decrease or even irreversible loss of vision.
To assess the effectiveness of predicting the development of PACG in eyes with short anterior-posterior axis.
The study included 69 patients (90 eyes) aged 46 to 80 years with short anterior-posterior axis. We used our own mathematical formulas for calculating the risk of PACG development. According to these formulas, two groups of patients with high risk of PACG were selected. Patients of the main group underwent cataract phacoemulsification for preventive purposes, while patients of the comparison group did not undergo any operative treatment.
In the long-term, PACG did not develop in the patients of the main group. Patients of the comparison group refused to undergo cataract phacoemulsification, and had PACG develop in 38% of cases in the long-term follow-up.
The high efficiency of the developed screening model for estimating the risk of PACG developing in eyes with short anterior-posterior axis has been proved. Preventive cataract phacoemulsification in the eyes with a high risk of PACG development in all cases helped to avoid it, retaining and even improving visual functions.
青光眼急性发作是眼部最严重的紧急情况之一,可导致无法治疗的失明。这种情况是眼流体动力学的急性失代偿,发生于原发性闭角型青光眼(PACG)。PACG仅在急性发作突然发生时可检测性高,急性发作可导致视力急剧下降甚至不可逆丧失。
评估预测短眼轴眼发生PACG的有效性。
研究纳入69例(90只眼)年龄46至80岁的短眼轴患者。我们使用自己的数学公式计算发生PACG的风险。根据这些公式,选择两组发生PACG风险高的患者。主要组患者为预防目的接受白内障超声乳化术,而对照组患者未接受任何手术治疗。
长期来看,主要组患者未发生PACG。对照组患者拒绝接受白内障超声乳化术,长期随访中38%的病例发生了PACG。
已证明所开发的筛查模型在评估短眼轴眼发生PACG风险方面具有高效性。在所有发生PACG风险高的眼中进行预防性白内障超声乳化术有助于避免其发生,保留甚至改善视功能。