老年患者肾活检评估。
Evaluation of kidney biopsies in elderly patients.
机构信息
Department of Nephrology, Marmara University Pendik Training and Research Hospital, Fevzi Çakmak Mahallesi, Muhsin Yazıcıoğlu Cd No: 10, 34899, Istanbul, Turkey.
Department of Nephrology, Agrı Public Hospital, Agrı, Turkey.
出版信息
Int Urol Nephrol. 2019 May;51(5):869-874. doi: 10.1007/s11255-019-02109-1. Epub 2019 Mar 4.
OBJECTIVE
The renal parenchymal disease spectrum in geriatric patients is similar to that in younger patients and can be controlled by appropriate treatment. We evaluated the clinicopathological features of kidney biopsies from geriatric patients.
MATERIALS AND METHODS
One hundred nine native kidney biopsies from older patients (> 65 years old) obtained from 2005 to 2014 were evaluated retrospectively. The specimens were inspected by the same pathologist in the same laboratory by light microscopy and immunofluorescence.
RESULTS
The mean age of the patients was 72.4 ± 7.8 years (range 65-90 years), and 51.3% were female. The most frequent indication for kidney biopsy was proteinuria at the nephrotic level (56.8%). The most frequent histopathological diagnoses were focal segmental glomerulosclerosis in primary glomerulonephritis and secondary amyloidosis in secondary glomerulonephritis. The rate of major complications due to kidney biopsy was < 1%.
RESULT
Kidney biopsy is an effective and safe method of evaluating renal parenchymal diseases in older patients.
目的
老年患者的肾实质疾病谱与年轻患者相似，可通过适当的治疗进行控制。我们评估了老年患者（>65 岁）肾活检的临床病理特征。
材料和方法
回顾性分析 2005 年至 2014 年间获得的 109 例老年患者（>65 岁）的 109 例肾活检标本。由同一位病理学家在同一家实验室通过光镜和免疫荧光检查标本。
结果
患者的平均年龄为 72.4±7.8 岁（65-90 岁），51.3%为女性。肾活检的主要适应证是肾病水平的蛋白尿（56.8%）。最常见的原发性肾小球肾炎的组织病理学诊断为局灶节段性肾小球硬化症，继发性肾小球肾炎的组织病理学诊断为继发性淀粉样变性。由于肾活检引起的主要并发症发生率<1%。
结果
肾活检是评估老年患者肾实质疾病的有效且安全的方法。
Zotero 插件