Filice G A, Andrews J S, Hudgins M P, Fraser D W
Am J Dis Child. 1978 Aug;132(8):757-9.
To determine the risk of severe secondary illness in household contacts of patients with Haemophilus influenzae meningitis, telephone interviews were conducted with contacts of patients with reported cases. Four probable or proved secondary cases of severe disease were identified for a secondary attack rate of 0.4%. The secondary attack rate for household contacts of patients 2 years of age and younger was 4.9%. Until safe, effective prophylactic measures become available, physicians should explain to parents that any person who becomes ill in the month after a household case of H influenzae meningitis should be brought to the attention of a physician for appropriate evaluation and treatment.
为确定流感嗜血杆菌性脑膜炎患者家庭接触者发生严重继发性疾病的风险,对报告病例的患者接触者进行了电话访谈。确定了4例可能或确诊的严重疾病继发病例,继发感染率为0.4%。2岁及以下患者的家庭接触者继发感染率为4.9%。在有安全、有效的预防措施之前,医生应向家长解释,在家庭中出现流感嗜血杆菌性脑膜炎病例后的一个月内,任何生病的人都应引起医生的注意,以便进行适当的评估和治疗。