蓝藻菌视紫红质：覆盖整个紫外线到可见光光谱的光受体。
Cyanobacteriochromes: photoreceptors covering the entire UV-to-visible spectrum.
机构信息
Graduate School of Integrated Science and Technology, Shizuoka University, 836 Ohya, Suruga, Shizuoka 422-8529, Japan; Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.
Graduate School of Integrated Science and Technology, Shizuoka University, 836 Ohya, Suruga, Shizuoka 422-8529, Japan; Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan; Research Institute of Green Science and Technology, Shizuoka University, 836 Ohya, Suruga, Shizuoka 422-8529, Japan.
出版信息
Curr Opin Struct Biol. 2019 Aug;57:39-46. doi: 10.1016/j.sbi.2019.01.018. Epub 2019 Mar 2.
Cyanobacteriochrome photoreceptors are linear tetrapyrrole-binding photoreceptors that are distantly related to the canonical phytochrome photoreceptors. The chromophore-binding region of the cyanobacteriochromes consists of only a cGMP-phosphodiesterase/adenylate cyclase/FhlA (GAF) domain, while that of the phytochromes consists of three domains, including the GAF domain. Most of the canonical phytochromes homogenously show red/far-red reversible photoconversion. Conversely, the cyanobacteriochrome photoreceptors are highly diverse in the colors of light they sense. Since the discovery of the first cyanobacteriochrome photoreceptor around 15 years ago, physiological, biochemical, and biophysical studies on cyanobacteriochromes have been extensively performed to date. In this review, we focus on color-tuning mechanisms of diverse cyanobacteriochromes.
蓝藻感光体是线性四吡咯结合光受体，与典型的光敏色素光受体有很远的关系。蓝藻感光体的发色团结合区域仅由 cGMP-磷酸二酯酶/腺苷酸环化酶/FhlA（GAF）结构域组成，而光敏色素的发色团结合区域由三个结构域组成，包括 GAF 结构域。大多数典型的光敏色素均匀地表现出红/远红可逆光转化。相反，蓝藻感光体在它们感知的光的颜色上高度多样化。自大约 15 年前发现第一个蓝藻感光体以来，迄今为止，已经对蓝藻感光体进行了广泛的生理学、生物化学和生物物理学研究。在这篇综述中，我们专注于不同蓝藻感光体的颜色调谐机制。
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