Kawaguchi A, Hirsh P D, Wolfgang T C, Mills A S, Lower R R
J Thorac Cardiovasc Surg. 1986 Apr;91(4):485-9.
A technique is presented for transplantation of the heart and left lung en bloc in the dog. In contrast to the erratic respiratory pattern that occurs in subprimate animals after total cardiopulmonary denervation, preservation of innervation to the native right lung results in a normal respiratory pattern in the dog and has allowed survival of one animal for 68 days. This model is proposed as potentially suitable for physiologic and immunologic studies of cardiopulmonary transplantation in the dog.
本文介绍了一种在犬类中进行心脏和左肺整块移植的技术。与灵长类以下动物全心肺去神经支配后出现的不稳定呼吸模式不同，保留对天然右肺的神经支配可使犬类保持正常呼吸模式，并且已有一只动物存活了68天。该模型被认为可能适用于犬类心肺移植的生理和免疫研究。
