Department of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre Zagreb, Kispaticeva 12, Zagreb 10000, Croatia.
Department of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre Zagreb, Kispaticeva 12, Zagreb 10000, Croatia.
Heart Fail Clin. 2019 Apr;15(2):147-158. doi: 10.1016/j.hfc.2018.12.012. Epub 2019 Feb 2.
Despite the rapid development of emerging imaging technologies, left ventricular ejection fraction represents the cornerstone of diagnosis, choice of treatment, and prognosis in heart failure. However, true myocardial function often remains underestimated or overestimated in different conditions underlying this heterogeneous syndrome. Changes in left ventricular size and left ventricular ejection fraction, termed reverse remodeling, are among the main goals of treatment in heart failure, aimed at halting or attenuating disease progression. The lack of effective therapeutic approaches in nearly one-half of the heart failure population highlights the need for integrating novel echocardiographic measures to better understand the underlying pathophysiologic mechanisms.
尽管新兴影像学技术发展迅速，但左心室射血分数仍然是心力衰竭诊断、治疗选择和预后判断的基石。然而，在这种异质性综合征的不同情况下，真正的心肌功能往往被低估或高估。左心室大小和左心室射血分数的变化，称为逆重构，是心力衰竭治疗的主要目标之一，旨在阻止或减缓疾病进展。近一半心力衰竭患者缺乏有效的治疗方法，这凸显了需要整合新的超声心动图指标来更好地了解潜在的病理生理机制。
