Cardiac, Thoracic and Vascular Department, University of Pisa, Pisa, Italy.
Cardiac, Thoracic and Vascular Department, University of Pisa, Pisa, Italy.
Heart Fail Clin. 2019 Apr;15(2):159-166. doi: 10.1016/j.hfc.2018.12.013. Epub 2019 Feb 10.
Several left ventricular geometric patterns have been described both in healthy and pathologic hearts. Left ventricular mass, wall thickness, and the ratio of wall thickness to radius are important measures to characterize the spectrum of left ventricular geometry. For clinicians, an increase in left ventricular mass is the hallmark of left ventricular hypertrophy. Although pathologic hypertrophy initially can be compensatory, eventually it may become maladaptive and evolve toward progressive left ventricular dysfunction and heart failure. In particular, patients who show left ventricular dilation and hypertrophy in association with a low relative wall thickness are likely to carry the highest risk.
已有研究描述了多种健康和病变心脏的左心室几何形态。左心室质量、室壁厚度和室壁厚度与半径的比值是描述左心室几何形态谱的重要指标。对于临床医生来说,左心室质量的增加是左心室肥厚的标志。尽管病理性肥厚最初可能是代偿性的,但最终可能会变得适应不良,并逐渐发展为进行性左心室功能障碍和心力衰竭。特别是那些伴有相对较低室壁厚度的左心室扩张和肥厚的患者,其风险可能最高。