Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.
Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia; AndroUrology Centre, Brisbane, QLD, Australia; Department of Urology, Macquarie University Hospital, Sydney, NSW, Australia.
Sex Med Rev. 2019 Apr;7(2):306-312. doi: 10.1016/j.sxmr.2018.12.006. Epub 2019 Mar 2.
Platelet-rich plasma (PRP) injections have recently been marketed as a form of autologous cell therapy under the banner of regenerative medicine despite limited scientific evidence on its use for treating erectile dysfunction (ED).
To evaluate the evidence on PRP treatment for ED and determine the current trends in provision of this treatment.
A critical review of the literature on PRP using the PubMed and Embase databases.
This narrative review focuses on the clinical use of, regulation of, and evidence for PRP in the treatment of ED.
There is a limited number of published peer-reviewed articles demonstrating clinical outcomes pertaining to the use of PRP for ED in human. The technique of PRP application for ED is currently patented, with a global total of 683 registered clinics. The majority of PRP clinics do not provide cost estimates on their websites.
Despite a global presence of PRP clinics and ongoing active marketing and public interest in regenerative medicine, no scientific evidence has been published to establish an evidence-based risk-benefit profile for PRP use for ED in humans. Given the limited data on clinical efficacy and potential harmful side effects, there is a need for a proper clinical trial to examine the role of PRP before it is accepted as standard of care in treatment for ED. Scott S, Roberts M, Chung E. Platelet-Rich Plasma and Treatment of Erectile Dysfunction: Critical Review of Literature and Global Trends in Platelet-Rich Plasma Clinics. Sex Med Rev 2019;7:306-312.
富含血小板的血浆 (PRP) 注射最近作为一种自体细胞疗法在再生医学的旗帜下销售，尽管其用于治疗勃起功能障碍 (ED) 的用途的科学证据有限。
评估 PRP 治疗 ED 的证据，并确定提供这种治疗的当前趋势。
使用 PubMed 和 Embase 数据库对 PRP 的文献进行批判性综述。
本文重点介绍了 PRP 在治疗 ED 中的临床应用、监管和证据。
尽管全球存在 PRP 诊所，并且再生医学的营销和公众兴趣持续活跃，但没有科学证据发表来确定 PRP 治疗 ED 的基于证据的风险效益概况。鉴于关于临床疗效和潜在有害副作用的有限数据，在将其接受为 ED 治疗的标准护理之前，需要进行适当的临床试验来检查 PRP 的作用。Scott S、Roberts M、Chung E. 富含血小板的血浆和治疗勃起功能障碍：文献综述和富含血小板的血浆诊所的全球趋势的批判性评论。性医学评论 2019;7:306-312。
