Department of Urology, University of Alexandria, Egypt.
Department of Urology, University of Alexandria, Egypt.
J Pediatr Urol. 2019 Apr;15(2):151.e1-151.e10. doi: 10.1016/j.jpurol.2019.01.002. Epub 2019 Jan 18.
Residual curvature, scarred or absent urethral plate, shortage of skin, and paucity of vascularized tissues and flaps are all obstacles to overcome during repair of redo and cripple hypospadias after failed reconstruction. Limited articles address the outcome of repair of these cases using different grafts.
An analysis of outcomes and complications after the repair of redo and cripple hypospadias in a cohort of children operated by a single surgeon is presented, and data are retrieved from a prospectively designed database.
Thirty-one children with a median age of 96 months (18-216, interquartile range [IQR]: 78), who underwent previous surgeries three to five times, were operated in the period from late 2011 to August 2017 in a single center by a single surgeon (first author); the first-stage repair was performed by using an inner prepuce graft in three children and oral grafts in 28 children. Penile straightening by degloving and removal of ventral scarred tissues are followed by development of glanular wings and grafting of the ventral surface.
Eleven distal penile hypospadias and 20 posterior hypospadias were operated. First-stage repair was revised in three children; 25 children, eight distal and 17 posterior hypospadias, underwent second-stage repair with a median age of 84 months (18-216, IQR: 60). The success rate after the second-stage repair was 56% (14 children), and complications were encountered in 11 children in the form of penoscrotal fistulae in four, complete dehiscence in one, and glanular dehiscence in six children. After closure of fistulae, the overall success rate increased to 72%. Although complications were more common among children with posterior hypospadias (nine children) than children with distal hypospadias (two children), no statistical significance was reached (p = .234), with no effect of age on complications (p = .233), no effect of the position of the meatus on glanular dehiscence (p = .624), and no effect of age on glanular dehiscence (p = .114).
Repair of redo and crippled hypospadias using staged graft repair in children could be achieved with a satisfactory overall success rate of 72%. Glanular dehiscence is the main complication; however, it is not considered by parents of children in the series, necessitating intervention. The lowest complication rate is expected among those with a position of the meatus more distal, however, not proven statistically in the series.
在修复多次重建失败后的 redo 和 cripple 型尿道下裂时,仍然存在残余弯曲、瘢痕化或缺失的尿道板、皮肤短缺、以及血管化组织和皮瓣不足等问题。有限的文献报道了使用不同移植物修复这些病例的结果。
本文分析了由一位外科医生对一组儿童 redo 和 cripple 型尿道下裂患者进行修复的结果和并发症,这些数据来自一个前瞻性设计的数据库。
31 名儿童的中位年龄为 96 个月(18-216,四分位距 [IQR]:78),他们曾接受过 3-5 次手术,均由同一位外科医生(第一作者)在 2011 年末至 2017 年 8 月期间在一个中心进行手术;一期修复中,3 名儿童采用内包皮移植物,28 名儿童采用口腔移植物。通过脱套和去除腹侧瘢痕组织来矫正阴茎弯曲,然后形成龟头翼并移植腹侧。
11 名远端阴茎型尿道下裂和 20 名后型尿道下裂患者接受了手术。有 3 名儿童需要进行一期修复修正,有 25 名儿童(8 名远端和 17 名后型)接受了中位年龄为 84 个月(18-216,IQR:60)的二期修复。二期修复的成功率为 56%(14 名儿童),11 名儿童出现并发症,表现为 4 例尿瘘、1 例完全裂开和 6 例龟头裂开。在闭合瘘管后,总体成功率增加到 72%。虽然后型尿道下裂患儿(9 名)的并发症比远端尿道下裂患儿(2 名)更常见,但差异无统计学意义(p=0.234),年龄对并发症无影响(p=0.233),尿道口位置对龟头裂开无影响(p=0.624),年龄对龟头裂开也无影响(p=0.114)。
对儿童进行分期移植物修复 redo 和 cripple 型尿道下裂,可以获得满意的总体成功率 72%。龟头裂开是主要并发症,但在本系列中,患儿家长并不认为这是一个问题,因此需要进行干预。然而,在本系列中,尿道口位置越远,预计并发症发生率越低,但尚未得到统计学证明。