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针刺治疗心房颤动患者疗效与安全性的系统评价

Systematic Evaluation of Efficacy and Safety of Acupuncture Treatment for Patients with Atrial Fibrillation.

作者信息

Fei Yu, Fei Rui, Zhang Jing, Sun Yaoyao, Yu Qiong

机构信息

Department of Cardiology, the Second Hospital, Jilin University, Changchun, Jilin 130041, China.

Department of Cell Biology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, China.

出版信息

Open Access Maced J Med Sci. 2019 Jan 26;7(3):461-466. doi: 10.3889/oamjms.2019.036. eCollection 2019 Feb 15.

DOI:10.3889/oamjms.2019.036
PMID:30834020
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6390133/
Abstract

BACKGROUND

Atrial fibrillation (AF) is one of the most common types of arrhythmia diagnosed in clinical practice. Due to its negative effects on people's physical and mental health, it is necessary to prevent and treat AF. Recently, scholars have found that acupuncture can be used to treat AF, but some scholars have questioned its therapeutic efficacy.

AIM

Therefore, this study was performed to assess the efficacy and safety of acupuncture treatment for AF patients.

METHODS

Previously published research articles were retrieved from six databases, and the data was analysed using RevMan5.3 software with a statistically significant difference defined as P < 0.05.

RESULTS

A total of 8 relevant kinds of literature were retrieved containing 633 AF patients (323 in the treatment group and 310 in the control group). Acupuncture treatment increased the total efficacy and the rate of AF cardioversion to sinus rhythm (RR: 1.38; 95% CI: 1.25 to 1.53 vs RR: 1.40;95% CI: 1.16 to 1.69; each P < 0.05), and decreased the time of AF cardioversion to sinus rhythm, the heart rate and incidence of adverse effects (RR: -3.95; 95% CI: -4.98 to -2.91 vs RR: -14.54; 95% CI: -24.09 to -5.00 vs RR: 0.48; 95% CI: 0.21 to 1.11, each P < 0.05). There was difference between retention time more and less than 30 minutes (I2 = 74.9%, P = 0.05). The funnel plot displayed a symmetrical and funnel-form shape, indicating low bias.

CONCLUSION

Acupuncture has a good therapeutic effect and safety profile on patients with AF, and its application in clinical practice should be considered.

摘要

背景

心房颤动(AF)是临床实践中诊断出的最常见心律失常类型之一。由于其对人们身心健康的负面影响,有必要对AF进行防治。近年来,学者们发现针刺可用于治疗AF,但也有部分学者对其治疗效果提出质疑。

目的

因此,本研究旨在评估针刺治疗AF患者的疗效和安全性。

方法

从六个数据库中检索先前发表的研究文章,并使用RevMan5.3软件进行数据分析,以P<0.05定义为具有统计学意义的差异。

结果

共检索到8篇相关文献,包含633例AF患者(治疗组323例,对照组310例)。针刺治疗提高了总有效率和AF转复为窦性心律的比率(RR:1.38;95%CI:1.25至1.53对比RR:1.40;95%CI:1.16至1.69;各P<0.05),并缩短了AF转复为窦性心律的时间、心率及不良反应发生率(RR:-3.95;95%CI:-4.98至-2.91对比RR:-14.54;95%CI:-24.09至-5.00对比RR:0.48;95%CI:0.21至1.11,各P<0.05)。留针时间大于和小于30分钟之间存在差异(I2=74.9%,P=0.05)。漏斗图呈对称的漏斗形状,表明偏倚较低。

结论

针刺对AF患者具有良好的治疗效果和安全性,应考虑在临床实践中应用。

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Update on atrial fibrillation.心房颤动最新进展
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