[Protein restriction and metabolism of xenobiotics].
作者信息
Albrecht R, Pelissier M A, Miladi N, Atteba S, Desfontaines C, Narbonne J F
出版信息
Ann Nutr Metab. 1986;30(2):73-80. doi: 10.1159/000177178.
PMID:3083760
Abstract
Young male rats were fed a balanced diet or a low-protein diet (casein 6%; w/w) for 6 weeks. After 2 weeks, each group was divided, one half being maintained as the control and the other half being fed diet-containing (Phenoclor DP6) at a level of 50 mg/kg for 4 weeks. A low-protein diet lowered the liver glutathione content and the activity of the mono-oxygenases. It lowered the inductive effect of PCB towards P450, NADPH-cytochrome c reductase, aminopyrine demethylase and aniline hydroxylase, but it raised the benzo(a) pyrene hydroxylase induction.
摘要
相似文献
1
[Protein restriction and metabolism of xenobiotics].
Ann Nutr Metab. 1986;30(2):73-80. doi: 10.1159/000177178.
2
[Polychlorobiphenyl (Phenoclor DP6) and the metabolism of xenobiotics: effect of a high lipid diet].
Food Chem Toxicol. 1985 Sep;23(9):805-8. doi: 10.1016/0278-6915(85)90280-7.
3
Postnatal development of mixed-function oxidation as measured in microsomes from the small intestine and liver of rabbits.兔小肠和肝脏微粒体中混合功能氧化的产后发育情况
Drug Metab Dispos. 1976 Jan-Feb;4(1):17-24.
4
Alterations in hepatic and splenic microsomal electron transport system components, drug metabolism, heme oxygenase activity, and cytochrome P-450 turnover in Murphy-Sturm lymphosarcoma-bearing rats.荷Murphy-Sturm淋巴肉瘤大鼠肝脏和脾脏微粒体电子传递系统成分、药物代谢、血红素加氧酶活性及细胞色素P-450周转率的改变
Cancer Res. 1982 Sep;42(9):3557-64.
5
Inductive effect of polychlorinated biphenyls mixture and individual isomers on the hepatic microsomal enzymes.多氯联苯混合物及个别异构体对肝脏微粒体酶的诱导作用。
Chem Pharm Bull (Tokyo). 1978 Apr;26(4):1215-21. doi: 10.1248/cpb.26.1215.
6
Influence of the oral contraceptive, menstranol, on drug-metabolizing enzymes of female rats in thiamin-supplemented and deficiency states.口服避孕药炔雌醇甲醚对硫胺素补充和缺乏状态下雌性大鼠药物代谢酶的影响。
Pharmacology. 1976;14(2):104-14. doi: 10.1159/000136586.
7
Interaction of endosulfan and dietary vitamin A on rat hepatic drug metabolising enzymes.硫丹与膳食维生素A对大鼠肝脏药物代谢酶的相互作用。
Acta Vitaminol Enzymol. 1983;5(4):213-8.
8
Activation of hepatic microsomal mixed function oxidase system in broiler chicks by diet changes.日粮变化对肉仔鸡肝脏微粒体混合功能氧化酶系统的激活作用。
Poult Sci. 1985 May;64(5):963-8. doi: 10.3382/ps.0640963.
9
[Reduction by dithiocarbamate fungicide, zineb, of the activity of oxygenases of the rat liver microsomes: effects of 9% casein regimen].[二硫代氨基甲酸盐类杀菌剂代森锌对大鼠肝微粒体加氧酶活性的降低作用：9%酪蛋白饮食方案的影响]
Food Cosmet Toxicol. 1981 Jun;19(3):357-60. doi: 10.1016/0015-6264(81)90396-5.
10
On the inhibition of microsomal drug metabolism by polychlorinated biphenyls (PCB) and related phenolic compounds.多氯联苯（PCB）及相关酚类化合物对微粒体药物代谢的抑制作用
Chem Biol Interact. 1977 Feb;16(2):191-200. doi: 10.1016/0009-2797(77)90128-4.
Zotero 插件