Gallinoro Emanuele, Papa Andrea Antonio, Rago Anna, Sperlongano Simona, Cassese Antonio, Cioppa Nadia Della, Magliocca Maria Cristina Giada, Cimmino Giovanni, Golino Paolo
Department of Cardiology, University of Campania "L. Vanvitelli", Monaldi Hospital, Naples, Italy.
Department of Anesthesiology, Monaldi Hospital, Naples, Italy.
Acta Myol. 2018 Sep 1;37(3):227-231. eCollection 2018 Sep.
Myotonic dystrophy type 1 (DM1) is the most common form of adult muscular dystrophy. It is an autosomal dominant inherited disease with multisystemic involvement. Respiratory function is often affected and respiratory failure is the most common cause of death. Pulmonary embolism is a rare cause of respiratory failure in DM1 patients, so that the best anticoagulation strategy in these patients is still unclear. We describe the case of pulmonary embolism in a DM1 patient, in which pulmonary thrombus was completely resolved with oral dabigatran etexilate therapy.
1型强直性肌营养不良（DM1）是成人肌营养不良最常见的形式。它是一种常染色体显性遗传病，会累及多个系统。呼吸功能常受影响，呼吸衰竭是最常见的死亡原因。肺栓塞是DM1患者呼吸衰竭的罕见原因，因此这些患者的最佳抗凝策略仍不明确。我们描述了1例DM1患者发生肺栓塞的病例，该患者口服达比加群酯治疗后肺血栓完全溶解。
