Department of Anesthesiology and Intensive Care, AJA University of Medical Sciences, Tehran, Iran.
Department of Internal Medicine, School of Medicine Sina Hospital Tehran University of Medical Sciences, Tehran, Iran.
J Cell Physiol. 2019 Aug;234(10):16944-16952. doi: 10.1002/jcp.28407. Epub 2019 Mar 6.
Various types of anesthesia are being utilized to maintain physiologically secured surgical conditions. Nearly all categories of general anesthesia are characterized by various perioperative and postoperative complications. These shortcomings are important aspects that need to be considered by the anesthesiologist and surgeon before administration of these compounds. The renal effects of anesthesia play an important role in understanding possible systemic changes due to the fact that the kidney has a direct or indirect impact on nearly all the systems of the body. Various studies have been conducted to find out changes in renal parameters and its systemic effects upon administration of the anesthesia and its postoperative repercussions. Besides that, the impaired renal function might have an impact on the excretion of anesthetic metabolites, which can lead to long-term dysfunction. Patients with a previous history of disease ought to be brought under consideration because these chemicals can ameliorate pre-existent symptoms. This review is intended to discuss the early and latest studies based on the effects of general anesthesia on the renal system.
各种类型的麻醉正在被用于维持生理安全的手术条件。几乎所有类别的全身麻醉都具有各种围手术期和术后并发症。这些缺点是麻醉师和外科医生在使用这些化合物之前需要考虑的重要方面。麻醉对肾脏的影响在理解由于肾脏对身体的几乎所有系统都有直接或间接影响而导致的可能的全身变化方面起着重要作用。已经进行了各种研究以发现麻醉给药及其术后影响时肾参数的变化及其对全身的影响。除此之外，肾功能受损可能会影响麻醉代谢物的排泄，这可能导致长期功能障碍。应该考虑有既往病史的患者，因为这些化学物质可以改善先前存在的症状。本篇综述旨在讨论基于全身麻醉对肾脏系统影响的早期和最新研究。
