Ozcan Irem Ozturk, Demirsoy Evren Odyakmaz, Sayman Nilgün, Akturk Aysun Sikar, Bayramgurler Dilek, Kiran Rebiay
a Department of Dermatology, Kocaeli University School of Medicine , Kocaeli , Turkey.
Cutan Ocul Toxicol. 2019 Sep;38(3):258-260. doi: 10.1080/15569527.2019.1590391. Epub 2019 Mar 25.
The aetiology of pigmented purpuric dermatoses is unclear. Recent studies speculate about contact sensitivity to play a role in the aetiology of the disease. In most patients, the lesions begin and stay limited on the lower extremities as textile products are in tight contact with the skin. Also, textile dyes can cause contact dermatitis of purpuric type. This study was conducted in order to understand whether the contact sensitivity plays a critical role in the aetiology of pigmented purpuric dermatoses. Patients with diagnosis of pigmented purpuric dermatoses were included in the study. Patch tests were applied at the back of all patients with textile series (Chemotechnique Diagnostics TF-1000) which have 33 allergens containing textile dyes, material and protectors by IQ Ultra Chamber. Test sites were evaluated at 48, 72, 96. h and on the 7th day according to the criteria of the International Contact Dermatitis Research Group. The evaluation results were recorded in patient files and the results were statistically compared. Eighteen males (60%) and 12 females (40%), a total of 30 patients were included in the study. Schamberg disease in 23 patients (76.7%), lichen aureus in 5 patients (16.7%) and Majocchi disease in 2 patients (6.7%) were described out of total 30 patients. No contact sensitivity was detected in any of the patients. Contact sensitivity to textile dyes was not found as an etiologic factor in our study group.
色素性紫癜性皮病的病因尚不清楚。最近的研究推测接触性敏感在该病的病因中起作用。在大多数患者中，由于纺织产品与皮肤紧密接触，皮损始于下肢并局限于此。此外，纺织染料可引起紫癜型接触性皮炎。本研究旨在了解接触性敏感在色素性紫癜性皮病的病因中是否起关键作用。诊断为色素性紫癜性皮病的患者被纳入研究。通过IQ Ultra Chambers对所有患者背部进行纺织物系列（Chemotechnique Diagnostics TF - 1000）的斑贴试验，该系列有33种含纺织染料、材料和防护剂的变应原。根据国际接触性皮炎研究组的标准，在48、72、96小时及第7天对试验部位进行评估。评估结果记录在患者病历中，并对结果进行统计学比较。本研究共纳入30例患者，其中男性18例（60%），女性12例（40%）。30例患者中，诊断为进行性色素性紫癜性皮病的有23例（76.7%），金黄色苔藓的有5例（16.7%），马约基病的有2例（6.7%）。所有患者均未检测到接触性敏感。在我们的研究组中，未发现对纺织染料的接触性敏感是一个病因学因素。
