Rovira Aleix, Nixon Iain J, Simo Ricard
Department of Otorhinolaryngology - Head and Neck Surgery, Head, Neck and Thyroid Oncology Unit, Guy's and St Thomas NHS Foundation Trust, London.
Department of Otolaryngology Head and Neck Surgery, NHS Lothian, Edinburgh.
Curr Opin Otolaryngol Head Neck Surg. 2019 Apr;27(2):110-116. doi: 10.1097/MOO.0000000000000520.
To highlight recent advances in our understanding of the nature of micropapillary thyroid carcinoma (mPTC), its evaluation and options of management based on risk.
A dramatic increase of the incidence of papillary thyroid carcinoma has been reported worldwide during recent decades, specifically those smaller than 10 mm (mPTC). Although not taking into consideration other risk factors for aggressiveness when describing tumours by their size, most of these newly diagnosed mPTC are indolent and active surveillance can be considered as valid option for their management.
An increasing number of patients with mPTC will be encountered in clinical practice. Although it is difficult to assess the aggressiveness of a tumour on size criteria, less than a total thyroidectomy and active surveillance can be considered for the majority of patients with mPTC. Further trials should be performed to prove this as a valid option of management in the majority of these patients.
强调我们对微乳头甲状腺癌（mPTC）本质的理解、评估及其基于风险的管理选择方面的最新进展。
近几十年来，全球范围内甲状腺乳头状癌的发病率显著上升，尤其是那些小于10毫米的（mPTC）。尽管在按肿瘤大小描述肿瘤时未考虑其他侵袭性风险因素，但大多数新诊断的mPTC生长缓慢，积极监测可被视为其管理的有效选择。
临床实践中将会遇到越来越多的mPTC患者。尽管根据大小标准难以评估肿瘤的侵袭性，但对于大多数mPTC患者，可考虑行次全甲状腺切除术和积极监测。应进行进一步试验以证明这是这些患者大多数的有效管理选择。
