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经微创腹式子宫骶骨固定术联合网片加强骶骨固定术治疗后盆腔器官脱垂复发和以患者为中心的结局

Pelvic Organ Prolapse Recurrence and Patient-Centered Outcomes Following Minimally Invasive Abdominal Uterosacral Ligament and Mesh-Augmented Sacrohysteropexy.

机构信息

From the Center for Urogynecology and Reconstructive Pelvic Surgery; Obstetrics, Gynecology, and Women's Health Institute, Cleveland Clinic, Cleveland, OH.

出版信息

Female Pelvic Med Reconstr Surg. 2020 Dec 1;26(12):763-768. doi: 10.1097/SPV.0000000000000710.

Abstract

OBJECTIVES

The objective of this study was to compare outcomes after minimally invasive uterosacral ligament hysteropexy (USLH) and mesh-augmented sacrohysteropexy (MSH) for women with uterovaginal prolapse including prolapse recurrence and long-term patient satisfaction.

METHODS

This was a retrospective cohort study with a cross-sectional survey component. The medical record was queried for perioperative data for patients undergoing USLH and MSH between 2004 and 2016. Pelvic organ prolapse (POP) recurrence was defined as bulge symptoms and/or retreatment with a pessary or surgery. A cross-sectional survey assessed for adverse events and used validated questionnaires to assess symptoms and improvement.

RESULTS

Ninety-seven patients met the inclusion criteria: 42 MSH and 55 USLH. Mean age was 48 ± 14 years. Patients undergoing MSH were older, had more advanced POP, and were less likely to undergo concurrent procedures. There were no differences in perioperative complications between groups; 22.7% (n = 22) of patients experienced POP recurrence with 8.3% (n = 8) undergoing repeat surgery. After controlling for preoperative differences, there was no difference in POP recurrence between groups. The incidence of sacrohysteropexy mesh exposure was 7% (n = 3). Sixty-one percent (n = 59) of patients completed the survey; median follow-up time was 104 (46-164) months. Forty-one percent of respondents reported bothersome pelvic floor symptoms. Bulge symptoms were more common after MSH (41% vs 10%, P = 0.006). Ninety-three percent of all patients reported improvement after surgery, which was not different between groups.

CONCLUSIONS

One in 5 patients experienced POP recurrence with fewer than 10% undergoing repeat surgery for recurrence. There does not seem to be a significant difference in the incidence of recurrence between MSH and USLH.

摘要

目的

本研究旨在比较经阴道网片骶骨固定术(USLH)和网片增强子宫骶骨固定术(MSH)治疗包括复发和长期患者满意度在内的女性阴道前壁膨出的结局。

方法

这是一项回顾性队列研究,具有横断面调查部分。检索了 2004 年至 2016 年间接受 USLH 和 MSH 的患者的围手术期数据。阴道前壁膨出(POP)复发定义为膨出症状和/或使用阴道托或手术再次治疗。横断面调查评估了不良事件,并使用经过验证的问卷评估了症状和改善情况。

结果

97 名患者符合纳入标准:42 名 MSH 和 55 名 USLH。平均年龄为 48±14 岁。接受 MSH 的患者年龄较大,POP 较严重,并且不太可能同时进行其他手术。两组之间的围手术期并发症无差异;22.7%(n=22)的患者出现 POP 复发,8.3%(n=8)的患者接受了再次手术。在控制术前差异后,两组之间 POP 复发无差异。骶骨固定术网片暴露的发生率为 7%(n=3)。61%(n=59)的患者完成了调查;中位随访时间为 104(46-164)个月。41%的受访者报告有令人烦恼的盆底症状。MSH 后膨出症状更常见(41%比 10%,P=0.006)。所有患者中有 93%报告手术后症状改善,两组之间无差异。

结论

1/5 的患者出现 POP 复发,不到 10%的患者因复发再次手术。MSH 和 USLH 之间复发的发生率似乎没有显著差异。

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