喉部罕见的良性肿瘤——喉淀粉样变性。

Rare benign tumor of the larynx - laryngeal amyloidosis.

作者信息

Horhat Ioana Delia, Balica Nicolae Constantin, Urechescu Horaţiu Constantin, Baderca Flavia, Poenaru Mărioara, Doroş Caius Ion, Moţ Ion Cristian, Boia Eugen Radu, Mogoantă Carmen Aurelia, Chioreanu Alexandru, Vlăescu Alexandru Nicolae, Sarău Cristian Andrei

机构信息

Department of Microscopic Morphology, "Victor Babeş" University of Medicine and Pharmacy, Timişoara, Romania;

出版信息

Rom J Morphol Embryol. 2018;59(4):1263-1268.

PMID:30845310

Abstract

We report a case of rare benign tumor of the larynx - amyloidosis of larynx - in a 52-year-old female who presented to the Department of Ear, Nose and Throat (ENT), Timişoara Municipal Hospital, Romania, with dysphonia. The patient's first presentation was in June 2012, with a polypoid formation localized on left vocal cord. The patient underwent a suspended microlaryngoscopy (SM) with tumor removal followed by histopathological examination, which revealed a laryngeal amyloidosis. The tumor recurred in 2013, 2014, 2016, 2017 and 2018. The patient underwent tracheotomy, followed by SM with endoscopic CO2 laser procedures, in order to remove the tumor and to ensure the airway. The follow-up was for six years. In May 2018, amyloid was located in subglottis, glottis and left false vocal fold. The patient needed five revision surgical procedures. The patient did not developed systemic amyloidosis during the follow-up period.

摘要

我们报告了一例罕见的喉部良性肿瘤——喉淀粉样变性病例，患者为一名52岁女性，因声音嘶哑就诊于罗马尼亚蒂米什瓦拉市立医院耳鼻喉科。患者首次就诊于2012年6月，左侧声带出现息肉样肿物。患者接受了支撑喉镜下肿瘤切除术，随后进行组织病理学检查，结果显示为喉淀粉样变性。肿瘤分别于2013年、2014年、2016年、2017年和2018年复发。为切除肿瘤并确保气道通畅，患者接受了气管切开术，随后进行了支撑喉镜下内镜二氧化碳激光手术。随访期为六年。2018年5月，淀粉样物质位于声门下、声门和左侧假声带。患者需要进行五次翻修手术。随访期间患者未发生系统性淀粉样变性。