Sobotka Lindsay A, Hake Timothy, Kelly Crystal, Mousa Luay
Department of Internal Medicine The Ohio State University Wexner Medical Center Columbus Ohio.
Department of Hematology The Ohio State Wexner Medical Center Columbus Ohio.
Clin Case Rep. 2018 Dec 16;7(2):251-253. doi: 10.1002/ccr3.1956. eCollection 2019 Feb.
Significant elevations in alpha-fetoprotein should raise suspicion for hepatocellular carcinoma as malignancies with metastasis to the liver can elevate the alpha-fetoprotein level but typically <300 ng/mL. Diagnosis should be confirmed with typical characteristics of hepatocellular carcinoma on imaging and or liver biopsy to confirm diagnosis.
甲胎蛋白显著升高应引起对肝细胞癌的怀疑,因为转移至肝脏的恶性肿瘤可使甲胎蛋白水平升高,但通常<300 ng/mL。诊断应通过影像学上肝细胞癌的典型特征和/或肝活检来确诊。