瓜尔胶、木质素和果胶对大鼠胃肠道中蛋白水解酶水平的影响：一项基于时间的研究。

Effect of guar gum, lignin and pectin on proteolytic enzyme levels in the gastrointestinal tract of the rat: a time-based study.

作者信息

Shah N, Mahoney R R, Pellett P L

出版信息

J Nutr. 1986 May;116(5):786-94. doi: 10.1093/jn/116.5.786.

DOI:10.1093/jn/116.5.786

Abstract

The effects of dietary pectin (P), guar gum (G) and lignin (L) on stomach emptying and potential levels of pepsin, trypsin and chymotrypsin during a 2-h period after force-feeding were investigated in growing rats. All of the fibers delayed stomach emptying by 21-26 min. Total potential pepsin activity over 2 h decreased for P (57%), G (44%) and L (20%). In the intestine, total potential trypsin activity over 2 h increased for L (16%) but decreased for P (21%). Total potential chymotrypsin activity over 2 h increased for L (54%) and G (39%). Sixteen to 21% of the variability in intestinal activity over time was statistically attributable to variation in the weight of intestinal contents. The results indicate that fiber components altered proteolytic enzyme levels in the gastrointestinal tract, but the decreased protein utilization previously observed with these fibers is probably not due to reduced levels of intestinal proteases.

摘要

在生长中的大鼠中，研究了日粮中的果胶（P）、瓜尔豆胶（G）和木质素（L）对强制喂食后2小时内胃排空以及胃蛋白酶、胰蛋白酶和糜蛋白酶潜在水平的影响。所有纤维均使胃排空延迟21 - 26分钟。2小时内总胃蛋白酶潜在活性，果胶（P）降低了57%，瓜尔豆胶（G）降低了44%，木质素（L）降低了20%。在肠道中，2小时内总胰蛋白酶潜在活性，木质素（L）增加了16%，而果胶（P）降低了21%。2小时内总糜蛋白酶潜在活性，木质素（L）增加了54%，瓜尔豆胶（G）增加了39%。随着时间推移，肠道活性中16%至21%的变异性在统计学上可归因于肠道内容物重量的变化。结果表明，纤维成分改变了胃肠道中蛋白水解酶的水平，但先前观察到的这些纤维导致蛋白质利用率降低，可能并非由于肠道蛋白酶水平降低。