临床分析中的毛细管电泳概述。

An Overview of CE in Clinical Analysis.

作者信息

Hage David S

机构信息

Department of Chemistry, University of Nebraska, Lincoln, NE, USA.

出版信息

Methods Mol Biol. 2019;1972:3-11. doi: 10.1007/978-1-4939-9213-3_1.

DOI:10.1007/978-1-4939-9213-3_1

PMID:30847780

Abstract

The development and general applications of capillary electrophoresis (CE) in the field of clinical chemistry are discussed. It is shown how the early development of electrophoresis was closely linked to clinical testing. The rise of gel electrophoresis in clinical chemistry is described, as well as the eventual developments that lead to the creation and the use of modern CE. The general principles of CE are reviewed and the potential advantages of this method in clinical testing are examined. Finally, an overview is presented of several areas in which CE has been developed and is currently being explored for use with clinical samples.

摘要

本文讨论了毛细管电泳（CE）在临床化学领域的发展及广泛应用。文中展示了电泳的早期发展如何与临床检测紧密相连。描述了凝胶电泳在临床化学中的兴起，以及最终促使现代CE产生和应用的发展历程。回顾了CE的一般原理，并探讨了该方法在临床检测中的潜在优势。最后，概述了CE已得到发展且目前正在探索用于临床样本检测的几个领域。