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新指南对儿童高血压患病率的影响:一项横断面评估。

The impact of new guidelines on the prevalence of hypertension in children: A cross-sectional evaluation.

机构信息

Department of Pediatrics, University of Oklahoma School of Community Medicine, Tulsa, Oklahoma.

Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Tulsa, Oklahoma.

出版信息

J Clin Hypertens (Greenwich). 2019 Apr;21(4):510-515. doi: 10.1111/jch.13512. Epub 2019 Mar 7.

Abstract

Updated clinical practice guidelines for screening blood pressures in pediatric patients were published in 2017. They differ from the previous guideline, known as the Fourth Report, providing updated population normal values and blood pressure categorization. We hypothesized that the prevalence of abnormal blood pressure in children and adolescents would be higher using the new clinical practice guidelines. We present a cross-sectional study of screening blood pressure values for children 3 to 18 years of age obtained during well-child visits at a primary care clinic. All blood pressure values were categorized using both the Fourth Report and the Clinical Practice Guideline. A total of 2635 blood pressure measurements were extracted, and 2600 were eligible for analysis. Using the clinical practice guideline, the prevalence of hypertension increased to 17.85% compared to 9.5% per the Fourth Report (P < 0.0001). Of those patients classified as having a normal blood pressure by the Fourth Report, 12% changed to abnormal when applying the Clinical Practice Guideline. All subgroups had a significant increase in the prevalence of abnormal blood pressure. The most dramatic increase in the prevalence of stage 1 and stage 2 hypertension was seen in six patient subgroups: males, 3-12 years of age, Hispanic ethnicity, race designated as other, normal weight, and overweight. Applying the new Clinical Practice Guideline increased the prevalence of elevated blood pressure and stage 1 and stage 2 hypertension in children and adolescents, requiring more follow-up and intervention than previously expected for this patient population.

摘要

2017 年发布了更新的儿科患者血压筛查临床实践指南。与之前的指南(第四报告)不同,它提供了更新的人群正常值和血压分类。我们假设使用新的临床实践指南,儿童和青少年的异常血压患病率会更高。我们报告了一项在初级保健诊所进行的儿童 3 至 18 岁的常规就诊时筛查血压值的横断面研究。所有血压值均使用第四报告和临床实践指南进行分类。共提取了 2635 次血压测量值,其中 2600 次符合分析条件。使用临床实践指南,高血压的患病率从第四报告的 9.5%增加到 17.85%(P<0.0001)。在第四报告中被归类为血压正常的患者中,有 12%在应用临床实践指南时变为异常。所有亚组的异常血压患病率均显著增加。在六个患者亚组中,男性、3-12 岁、西班牙裔、其他种族、正常体重和超重,高血压和 1 期和 2 期高血压的患病率显著增加。应用新的临床实践指南增加了儿童和青少年高血压和 1 期和 2 期高血压的患病率,需要比以前预期的更多的随访和干预。

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