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基于重复测量的学龄儿童高血压患病率及其与超重的关联

Prevalence of hypertension in schoolchildren based on repeated measurements and association with overweight.

作者信息

Chiolero Arnaud, Cachat François, Burnier Michel, Paccaud Fred, Bovet Pascal

机构信息

Community Prevention Unit, Institute of Social and Preventive Medicine, University Hospital Center, University of Lausanne, Switzerland , Switzerland.

出版信息

J Hypertens. 2007 Nov;25(11):2209-17. doi: 10.1097/HJH.0b013e3282ef48b2.

Abstract

OBJECTIVE

Most studies assess the prevalence of hypertension in pediatric populations based on blood pressure (BP) readings taken on a single visit. We determined the prevalence of hypertension measured on up to three visits in a Swiss pediatric population and examined the association between hypertension and overweight and selected other factors.

METHODS

Anthropometric data and BP were measured in all children of the sixth school grade of the Vaud canton (Switzerland) in 2005-2006. 'Elevated BP' was defined according to sex-specific, age-specific and height-specific US reference data. BP was measured on up to two additional visits in children with elevated BP. 'Hypertension' was defined as 'elevated BP' on all three visits.

RESULTS

Out of 6873 children, 5207 (76%) participated [2621 boys, 2586 girls; mean (SD) age, 12.3 (0.5) years]. The prevalence of elevated BP was 11.4, 3.8 and 2.2% on first, second and thirds visits, respectively; hence 2.2% had hypertension. Among hypertensive children, 81% had isolated systolic hypertension. Hypertension was associated with excess body weight, elevated heart rate and parents' history of hypertension. Of the children, 16.1% of boys and 12.4% of girls were overweight or obese (CDC criteria, body mass index >or= 85th percentile). Thirty-seven percent of cases of hypertension could be attributed to overweight or obesity.

CONCLUSIONS

The proportion of children with elevated BP based on one visit was five times higher than based on three measurements taken at few-week intervals. Our data re-emphasize the need for prevention and control of overweight in children to curb the global hypertension burden.

摘要

目的

大多数研究基于单次就诊时的血压读数评估儿科人群中高血压的患病率。我们确定了瑞士儿科人群中最多三次就诊时测量的高血压患病率,并研究了高血压与超重及其他选定因素之间的关联。

方法

对2005 - 2006年瑞士沃州六年级所有在校儿童进行人体测量数据和血压测量。“血压升高”根据美国特定性别、年龄和身高的参考数据定义。血压升高的儿童最多再进行两次就诊测量。“高血压”定义为三次就诊时均“血压升高”。

结果

6873名儿童中,5207名(76%)参与研究[2621名男孩,2586名女孩;平均(标准差)年龄12.3(0.5)岁]。首次、第二次和第三次就诊时血压升高的患病率分别为11.4%、3.8%和2.2%;因此,2.2%的儿童患有高血压。在高血压儿童中,81%为单纯收缩期高血压。高血压与体重超标、心率加快及父母高血压病史有关。在这些儿童中,16.1%的男孩和12.4%的女孩超重或肥胖(根据美国疾病控制与预防中心标准,体重指数≥第85百分位数)。37%的高血压病例可归因于超重或肥胖。

结论

基于单次就诊血压升高的儿童比例比间隔几周进行三次测量时高出五倍。我们的数据再次强调了预防和控制儿童超重以减轻全球高血压负担的必要性。

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