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射频子宫内膜消融术——月经过多保守治疗的新方法

Radiofrequency endometrial ablation - new possibility of heavy menstrual bleeding conservative treatment.

作者信息

Huser M, Papíková Z, Dziakova M, Hudeček R, Ventruba P

出版信息

Ceska Gynekol. 2018 Winter;83(6):418-423.

Abstract

OBJECTIVE

Evaluation of radiofrequency endometrial ablation (RFEA) clinical efficacy in patients with heavy menstrual bleeding (HMB).

DESIGN

Original article.

SETTING

Department of Gynecology and Obstetrics, University Hospital and Masaryk University Medical School, Brno.

METHODS

Study included 20 patients with HMB who had failed hormonal therapy and met the study inclusion criteria. All RFEA procedures were performed in the operating theater in general anesthesia by two experienced surgeons according to a standardized protocol. All RFEA were performed using specific disposable electrodes and radio frequency generator M-3004 (RF Medical Co., South Korea). Study outcomes were evaluated three months post-surgery included percentage of women with amenorrhoea or menstrual bleeding persistence measured by the modified Pictorial Blood Assessment Chart (PBAC) score. Furthermore, chronic pelvic pain intensity assessed by visual analogue scale (VAS), patient satisfaction (Patient Global Impression of Improvement, PGI-I score), and the incidence of complications were evaluated.

RESULTS

All RFEAs were performed without operational or technical complications, the average age being operated was 43.0 ± 2.9 years and the operating time did not exceed ten minutes. In the early postoperative follow-up, patients did not require any analgesics and were all released to outpatient care the following day. Percentage of amenorrhea at three months post-treatment was 35.0%, mean PBAC score for women with menstrual bleeding was 1.8 ± 0.6. Patients satisfaction with the treatment was evaluated by 1.6 ± 0.6 on the PGI-I scale and long-term pelvic pain was on average 2.1 ± 0.8 by VAS, which counts an improvement of 31.0%.

CONCLUSION

The HMB treatment with RFEA achieves good clinical results in three-month evaluation with objective and also subjective parameters. The technique is suitable for outpatient treatment and is an alternative to hysteroscopy endometrial ablation. Its wider clinical usage is limited by the high cost of the radiofrequency generator and disposable probes. Keywords heavy menstrual bleeding, hysteroscopy, radiofrequency endometrial ablation, amenorrhoea, complication.

摘要

目的

评估射频子宫内膜消融术(RFEA)治疗月经过多(HMB)患者的临床疗效。

设计

原创文章。

地点

布尔诺大学医院和马萨里克大学医学院妇产科。

方法

研究纳入20例月经过多且激素治疗无效并符合研究纳入标准的患者。所有RFEA手术均由两名经验丰富的外科医生在手术室全身麻醉下按照标准化方案进行。所有RFEA手术均使用特定的一次性电极和M - 3004射频发生器(韩国RF Medical公司)。术后三个月评估研究结果,包括通过改良的图片式出血量评估图(PBAC)评分测量的闭经或月经持续出血女性的百分比。此外,通过视觉模拟量表(VAS)评估慢性盆腔疼痛强度、患者满意度(患者总体改善印象,PGI - I评分),并评估并发症发生率。

结果

所有RFEA手术均未出现操作或技术并发症,手术平均年龄为43.0±2.9岁,手术时间不超过10分钟。术后早期随访中,患者无需任何止痛药物,次日均出院接受门诊治疗。治疗后三个月闭经百分比为35.0%,月经出血女性的平均PBAC评分为1.8±0.6。患者对治疗的满意度在PGI - I量表上评分为1.6±0.6,长期盆腔疼痛通过VAS平均评分为2.1±0.8,改善率为31.0%。

结论

在三个月的评估中,RFEA治疗月经过多在客观和主观参数方面均取得了良好的临床效果。该技术适用于门诊治疗,是宫腔镜子宫内膜消融术的一种替代方法。其更广泛的临床应用受到射频发生器和一次性探头高成本的限制。关键词月经过多、宫腔镜检查、射频子宫内膜消融术、闭经、并发症

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