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评估丙型肝炎或非酒精性脂肪性肝病患者的肝纤维化而无需进行肝活检。

Assessing liver fibrosis without biopsy in patients with HCV or NAFLD.

机构信息

Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH, USA.

Director, Hepatobiliary Pathology, Department of Pathology, Cleveland Clinic, Cleveland, OH, USA.

出版信息

Cleve Clin J Med. 2019 Mar;86(3):179-186. doi: 10.3949/ccjm.86a.17118.

DOI:10.3949/ccjm.86a.17118
PMID:30849036
Abstract

Staging of liver fibrosis is increasingly done using noninvasive methods, in some cases obviating the need for liver biopsy. Scores based on laboratory values and demographic variables have been developed and validated for assessing fibrosis in patients with hepatitis C virus (HCV) infection and nonalcoholic fatty liver disease (NAFLD), as have several imaging methods that measure shear-wave velocity, a reflection of fibrosis severity.

摘要

肝纤维化的分期越来越多地采用非侵入性方法,在某些情况下可以避免肝活检。已经开发和验证了基于实验室值和人口统计学变量的评分系统,用于评估丙型肝炎病毒 (HCV) 感染和非酒精性脂肪性肝病 (NAFLD) 患者的纤维化,还有几种测量剪切波速度的影像学方法,剪切波速度反映了纤维化的严重程度。

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