Meeroff J C
Med Hypotheses. 1986 Feb;19(2):93-9. doi: 10.1016/0306-9877(86)90049-6.
An eclectic theory of ulcer etiopathogenesis is presented. Its objective is to give a rational explanation to most of the disturbances and changes occurring in ulcer patients. The theory highlights the intricate cellular mechanisms which keep the balance between acid aggression and mucosal defense. The new theory presented here will serve as the skeletal framework upon which new biomedical and biopsychosocial development can be added to improve and expand the scientific explanation of why and how ulcers are formed.
本文提出了一种综合性的溃疡病因发病机制理论。其目的是对溃疡患者出现的大多数紊乱和变化作出合理的解释。该理论强调了维持胃酸侵袭与黏膜防御之间平衡的复杂细胞机制。这里提出的新理论将作为一个框架基础，在此基础上可以增添新的生物医学和生物心理社会学进展，以改进和扩展对溃疡形成原因及方式的科学解释。
