土拉弗朗西斯菌亚种 holarctica 引起的实体器官移植受者严重感染：两例报告及文献复习。
Severe infections due to Francisella tularensis ssp. holarctica in solid organ transplant recipient: report of two cases and review of literature.
机构信息
Department of Internal Medicine and Infectious Diseases, University Hospital of Tours, Hospital Bretonneau, 2, boulevard Tonnellé, 37044, Tours Cedex 9, France.
François Rabelais University, Tours, France.
出版信息
BMC Infect Dis. 2019 Mar 8;19(1):238. doi: 10.1186/s12879-019-3863-0.
BACKGROUND
Tularemia is a rare zoonotic infection caused by bacterium Francisella tularensis. It has been well described in immunocompetent patients but poorly described in immunocompromised patients notably in solid organ transplant recipients.
CASE PRESENTATIONS
We report here two cases of tularemia in solid organ transplant recipients including first case after heart transplant. We also carried out an exhaustive review of literature describing characteristics of this infection in solid organ transplant recipients.
背景
土拉热是一种由弗朗西斯菌引起的罕见人畜共患病感染。它在免疫功能正常的患者中已有很好的描述，但在免疫功能低下的患者中，尤其是实体器官移植受者中，描述较少。
病例介绍
我们在此报告了 2 例实体器官移植受者中的土拉热病例，包括首例心脏移植后病例。我们还对描述实体器官移植受者中这种感染特征的文献进行了详尽的回顾。
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