Martín Serrano P, Martín Hernández J G, Martín Celemín R, de Antonio Antón N, Orús García R, Planas Roca A
Servicio de Anestesiología y Reanimación, Hospital Universitario de La Princesa, Madrid, España.
Servicio de Anestesiología y Reanimación, Hospital Universitario de La Princesa, Madrid, España.
Rev Esp Anestesiol Reanim (Engl Ed). 2019 Jun-Jul;66(6):346-349. doi: 10.1016/j.redar.2019.01.008. Epub 2019 Mar 5.
Mastocytosis is a disease characterised by an abnormal proliferation of mast cells. The degranulation of mast cells can be triggered by chemical, physical, and psychological factors, and in severe cases may be accompanied by cardiovascular alterations and shock. Tryptase concentrations greater than 20ug/L may be associated with an increased risk of mastocyte degranulation. The case is presented on a 71 year-old man that underwent an aortic valve replacement and aortic-coronary bypass surgery. He had an indolent systemic mastocytosis and a history of histaminergic crises, with a baseline value of tryptase prior to surgery of 58.1ug/L.
肥大细胞增多症是一种以肥大细胞异常增殖为特征的疾病。肥大细胞的脱颗粒可由化学、物理和心理因素触发，严重时可能伴有心血管改变和休克。类胰蛋白酶浓度大于20μg/L可能与肥大细胞脱颗粒风险增加有关。本文介绍了一名71岁男性患者，他接受了主动脉瓣置换术和主动脉-冠状动脉搭桥手术。他患有惰性系统性肥大细胞增多症，有组胺能危象病史，术前类胰蛋白酶基线值为58.1μg/L。
